S
Sylvia Kleta
Researcher at Free University of Berlin
Publications - 7
Citations - 558
Sylvia Kleta is an academic researcher from Free University of Berlin. The author has contributed to research in topics: Escherichia coli & Population. The author has an hindex of 5, co-authored 5 publications receiving 500 citations. Previous affiliations of Sylvia Kleta include Federal Institute for Risk Assessment.
Papers
More filters
Journal ArticleDOI
Characterization of a porcine intestinal epithelial cell line for in vitro studies of microbial pathogenesis in swine
Peter Schierack,Marcel Nordhoff,Marion Pollmann,Karl Dietrich Weyrauch,Salah Amasheh,Ulrike Lodemann,Jörg Jores,Babila Tachu,Sylvia Kleta,Anthony T. Blikslager,Karsten Tedin,Lothar H. Wieler +11 more
TL;DR: The permanent porcine intestinal epithelial cell line, IPEC-J2, is characterized using a variety of methods to assess the usefulness of this cell line as an in vitro infection model and concludes that it provides a relevant in vitro model system for porCine intestinal pathogen–host cell interactions.
Journal ArticleDOI
Virulence Factor Gene Profiles of Escherichia coli Isolates from Clinically Healthy Pigs
TL;DR: The results appear to indicate that virulence gene-carrying E. coli strains are a normal part of intestinal bacterial populations and that high numbers of E. Escherichia coli cells harboring virulence genes and/or with hemolytic activity do not necessarily correlate with disease.
Journal ArticleDOI
Detection and distribution of probiotic Escherichia coli Nissle 1917 clones in swine herds in Germany
Sylvia Kleta,H. Steinrück,Gerhard Breves,S. Duncker,Claudia Laturnus,Lothar H. Wieler,Peter Schierack +6 more
TL;DR: To verify the presence of Escherichia coli Nissle 1917 as a natural isolate in swine and to characterize in vitro probiotic properties as well as in vivo persistence in a feeding experiment.
Journal ArticleDOI
E. coli Nissle 1917 Affects Salmonella Adhesion to Porcine Intestinal Epithelial Cells
Peter Schierack,Sylvia Kleta,Sylvia Kleta,Karsten Tedin,Julius Tachu Babila,Sibylle Oswald,Tobias A. Oelschlaeger,Rico Hiemann,Susanne Paetzold,Lothar H. Wieler +9 more
TL;DR: It is proposed that EcN affects Salmonella adhesion through secretory components, which appears to be common to many E. coli strains, with strong adherence being a prerequisite for an effective reduction of SiiE-mediated Salmoneella adhesion.
Journal ArticleDOI
Role of F1C Fimbriae, Flagella, and Secreted Bacterial Components in the Inhibitory Effect of Probiotic Escherichia coli Nissle 1917 on Atypical Enteropathogenic E. coli Infection
Sylvia Kleta,Marcel Nordhoff,Karsten Tedin,Lothar H. Wieler,Rafał Kolenda,Rafał Kolenda,Sibylle Oswald,Tobias A. Oelschlaeger,Wilfried Bleiß,Peter Schierack,Peter Schierack +10 more
TL;DR: It is proposed that the strong adhesion capacities enable EcN to secrete sufficient local concentrations of the inhibitory factors to reduce the infection efficiencies of aEPEC by inhibiting bacterial adhesion and growth of microcolonies, but not the attaching and effacing of adherent bacteria.