T
T.C. Tai
Researcher at Laurentian University
Publications - 22
Citations - 678
T.C. Tai is an academic researcher from Laurentian University. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 9, co-authored 16 publications receiving 561 citations. Previous affiliations of T.C. Tai include Northern Ontario School of Medicine.
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Journal ArticleDOI
Polyphenols: Benefits to the Cardiovascular System in Health and in Aging
TL;DR: This review highlights the literature surrounding this topic on the prominently studied and documented polyphenols as pertaining to cardiovascular health and aging.
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Oxidative stress in aging--matters of the heart and mind.
TL;DR: This review summarizes findings in the literature on oxidative stress and consequent damage on cells and tissues of the cardiovascular system and the central nervous system, with a focus on aging-related diseases that have well-documented evidence of oxidative damage in initiation and/or progression of the disease.
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Protective effects of methyl gallate on H2O2-induced apoptosis in PC12 cells.
James Crispo,Matthew Piche,Matthew Piche,Dominique Ansell,Dominique Ansell,Joseph K. Eibl,Joseph K. Eibl,Isabella T. Tai,Isabella T. Tai,Aseem Kumar,Aseem Kumar,Gregory M. Ross,Gregory M. Ross,T.C. Tai +13 more
TL;DR: Findings confirm the involvement of both intrinsic and extrinsic apoptotic pathways in H(2)O(2)-induced apoptosis and suggest that MG may have potential therapeutic properties against mitochondria-mediated apoptosis.
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Inflammatory Signaling in Hypertension: Regulation of Adrenal Catecholamine Biosynthesis.
TL;DR: The immune system has an active role in the progression of hypertension and cytokines are powerful modulators of adrenal cell function, and the role of cytokines in the coordination of blood pressure regulation and the stress response is discussed.
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Regulation of the phenylethanolamine N-methyltransferase gene in the adrenal gland of the spontaneous hypertensive rat
Phong Thanh Nguyen,Heather Peltsch,Jose de Wit,James Crispo,Gino Ubriaco,Joe Eibl,T.C. Tai,T.C. Tai +7 more
TL;DR: Investigation of the molecular mechanisms involved in the dysregulation of adrenal PNMT in the spontaneous hypertensive rat (SHR) in comparison to Wistar-Kyoto (WKY) normotensive controls demonstrates changes in key transcription factors regulating PnMT expression within the SHR adrenal gland, coincident with elevated adrenalPNMT expression.