T
Takashi Nomura
Researcher at Kyoto University
Publications - 160
Citations - 28462
Takashi Nomura is an academic researcher from Kyoto University. The author has contributed to research in topics: Medicine & Cytotoxic T cell. The author has an hindex of 34, co-authored 141 publications receiving 26095 citations. Previous affiliations of Takashi Nomura include Daikin & Takeda Pharmaceutical Company.
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Journal ArticleDOI
Abl family tyrosine kinases govern IgG extravasation in the skin in a murine pemphigus model
Sachiko Ono,Gyohei Egawa,Takashi Nomura,Akihiko Kitoh,Teruki Dainichi,Atsushi Otsuka,Saeko Nakajima,Masayuki Amagai,Fumi Matsumoto,Mami Yamamoto,Yoshiaki Kubota,Toshiyuki Takai,Tetsuya Honda,Kenji Kabashima,Kenji Kabashima +14 more
TL;DR: It is shown that IgG extravasation in the skin is mediated by endothelial caveolin transport independently of FcR, and is targetable by imatinib, which reduces IgG-dependent pathology in a mouse model of pemphigus.
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SLAM family member 8 is involved in oncogenic KIT-mediated signalling in human mastocytosis.
Akihiko Sugimoto,Tatsuki R. Kataoka,Chiyuki Ueshima,Yusuke Takei,Kyohei Kitamura,Masahiro Hirata,Takashi Nomura,Hironori Haga +7 more
TL;DR: SLAMF8 is involved in oncogenic KIT‐mediated RAS‐RAF‐ERK signalling and the subsequent growth of human neoplastic mast cells mediated by SHP‐2, and is a possible therapeutic target in human mastocytosis patients.
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Case of Conradi-Hünermann-Happle syndrome with alopecia: Histological examination of affected follicles.
Moyu Yajima,Eri Muroga,Takashi Nomura,Akiko Arakawa,Kenzo Takahashi,Kunihiko Matsubara,Kenji Kabashima,Yoshiki Miyachi +7 more
TL;DR: A female infant born spontaneously after an uneventful pregnancy exhibited symptoms of transient ichthyosis, short stature, alopecia, cataracts, hyperpigmentation and hypopigmentation with atrophic streaks of the skin, and minor asymmetrical shortening of the right thighbone, consistent with CHH syndrome.
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Construction of a T cell receptor signaling range for spontaneous development of autoimmune disease
Atsushi Tanaka,Shinji Maeda,Takashi Nomura,Mara Anaís Llamas-Covarrubias,Satoshi Tanaka,Lin Jin,Ee Lyn Lim,Hiromasa Morikawa,Yohko Kitagawa,Shuji Akizuki,Yoshinaga Ito,Chihiro Fujimori,Keiji Hirota,Tosei Murase,Motomu Hashimoto,Junichi Higo,Rose Zamoyska,Ryuzo Ueda,Daron M. Standley,Noriko Sakaguchi,Shimon Sakaguchi +20 more
TL;DR: In this article , the authors showed that reduction of ZAP-70 to a critical range produces autoimmune T cells and impairs Treg function, together eliciting autoimmune arthritis and colitis in mice.
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A Mild Case of Adult-Onset Keratosis Lichenoides Chronica Successfully Treated with Narrow-Band UVB Monotherapy.
TL;DR: Adult-onset KLC, which was treated by narrow-band ultraviolet B (NB-UVB) monotherapy, is presented and it is assumed that KLC is treatable by NB-UVBs regardless of the age of the patient.