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Takeshi Yoshimatsu

Researcher at University of Sussex

Publications -  52
Citations -  2001

Takeshi Yoshimatsu is an academic researcher from University of Sussex. The author has contributed to research in topics: Retina & Visual space. The author has an hindex of 17, co-authored 48 publications receiving 1571 citations. Previous affiliations of Takeshi Yoshimatsu include University of Tokyo & University of Washington.

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Hes binding to STAT3 mediates crosstalk between Notch and JAK–STAT signalling

TL;DR: It is shown that STAT3 is activated in the presence of active Notch, as well as the Notch effectors Hes1 and Hes5, thus promoting STAT3 phosphorylation and activation, and suppression of endogenous Hes1 expression reduces growth factor induction of STAT3osphorylation.
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Stimulation of functional neuronal regeneration from Müller glia in adult mice

TL;DR: It is shown that MG-specific overexpression of Ascl1, together with a histone deacetylase inhibitor, enables adult mice to generate neurons from MG after retinal injury, providing a new approach for the treatment of blinding retinal diseases.
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Zebrafish Differentially Process Color across Visual Space to Match Natural Scenes.

TL;DR: It is shown that larval zebrafish use a highly anisotropic retina to asymmetrically survey their natural visual world, with different neurons dominate different parts of the eye and are linked to a systematic shift in inner retinal function.
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Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex

TL;DR: A previously unrecognized mechanism of interaction between the JAK-STAT3 and DLL1-Notch signaling pathways, as well as a pivotal role for this interaction in maintenance of NPCs during early neocortical development are revealed.
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Müller glia provide essential tensile strength to the developing retina.

TL;DR: When the formation of Müller glia is inhibited in the zebrafish retina, a major consequence is that the retina begins to rip apart due to a loss of the mechanical resilience that these glial cells provide to the neural tissue.