Tamires Cardoso Lima

TL;DR: The results suggest that the presence of functional groups in the chemical structure of rotundifolone is not essential for its vasorelaxant activity, and both oxygenated terpenes and non-oxygenated terpene exhibit relaxation activity.

TL;DR: All evaluated monoterpenes, especially (−)-perillyl alcohol, have remarkable larvicidal effects and may be considered as potential sources for the development of suitable natural larvicides for mosquito management programs.

TL;DR: The results of molecular docking indicate that the presence of the enoate moiety along with hydroxyl and one methoxy substitution in the phenyl ring has a positive effect on the bioactivity of compound 7 against Candida albicans, which further support the hypothesis that the antifungal activity of compounds 7 could be due to its binding to multiple targets, specifically to QR, TS, and ST-PK.

TL;DR: The use of nanotechnology in medicine in particular, specifically drug delivery is shown to have various benefits as discussed by the authors, where nanoparticles are being used to reduce toxicity and side effects that drugs may impose to the patient.

TL;DR: The findings reveal antiproliferative potential of MCEO, its major component ROT, and its tested analogues and some of these chemical analogues may be useful as prototypes for the development of novel chemotherapeutic agents for treating human brain cancer and/or other cancers.