Tania Aguirre

TL;DR: Two families with ALS and one apparently sporadic ALS patient who are heterozygous for the D90A mutation are described, and one patient had the unusual phenotype of focal nonprogressing motor neuron disease.

TL;DR: The results suggest that the mechanism underlying both SOD1‐FALS and SALS jeopardizes the cell's defense against free radical stress, and that SOD 1‐F ALS cells are particularly sensitive to H2O2.

TL;DR: One important factor associated with the antiproliferative effects of ajoene against T. cruzi is its specific alteration of the phospholipid composition of these cells, particularly the mitochondrion and endoplasmatic reticulum.

TL;DR: The phenotype of 2 brothers with juvenile focal amyotrophy of the upper extremity was compared to that of 375 patients described in the Western literature and the 5 exons of the S OD1 gene were normal, as was the SOD activity in red blood cells.

TL;DR: The immunoelectron microscopy allowed us to show that the antigen(s) carrying the epitope reacting with mAb Tcr7 is (are) released in association with membrane vesicles which protruded from the parasite surface and the flagellar pocket, likely to be independent of phospholipase C‐mediated release of GPI‐anchored molecules.