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Petra Tilkin

Researcher at Katholieke Universiteit Leuven

Publications -  11
Citations -  1235

Petra Tilkin is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Amyotrophic lateral sclerosis & Superoxide dismutase. The author has an hindex of 8, co-authored 11 publications receiving 989 citations. Previous affiliations of Petra Tilkin include Vita-Salute San Raffaele University.

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Journal ArticleDOI

Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

James F. Howard, +623 more
- 01 Dec 2017 - 
TL;DR: A phase 3, randomised, double-blind, placebo-controlled, multicentre study in 76 hospitals and specialised clinics across North America, Latin America, Europe, and Asia to assess the efficacy and safety of eculizumab in patients with refractory myasthenia gravis.
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Minocycline delays disease onset and mortality in a transgenic model of ALS.

Ludo Van Den Bosch, +3 more
- 12 Jun 2002 - 
TL;DR: Results demonstrate that interference with immuno-inflammatory responses has a beneficial effect in the ALS mice model, suggesting this to be a potential new strategy to treat ALS.
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Neurofilament markers for ALS correlate with extent of upper and lower motor neuron disease.

Koen Poesen, +26 more
- 13 Jun 2017 - 
TL;DR: This study provides Class II evidence that elevated concentrations of CSF pNfH and NfL can accurately identify patients with ALS and shows an added value as diagnostic biomarkers for ALS, whereas the prognostic value of pNFH andNfL warrants further investigation.
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D90A heterozygosity in the SOD1 gene is associated with familial and apparently sporadic amyotrophic lateral sclerosis

Wim Robberecht, +5 more
- 01 Nov 1996 - 
TL;DR: Two families with ALS and one apparently sporadic ALS patient who are heterozygous for the D90A mutation are described, and one patient had the unusual phenotype of focal nonprogressing motor neuron disease.
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The G93C Mutation in Superoxide Dismutase 1: Clinicopathologic Phenotype and Prognosis

Luc Régal, +6 more
- 01 Feb 2006 - 
TL;DR: These findings add to the knowledge of S OD1-related familial ALS and demonstrate further clinicopathologic variability between different SOD1 mutations, and demonstrate the independent prognostic value of the G93C mutation.