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Tatiana I. Merkulova

Researcher at Russian Academy of Sciences

Publications -  16
Citations -  247

Tatiana I. Merkulova is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Single-nucleotide polymorphism & Gene. The author has an hindex of 7, co-authored 16 publications receiving 156 citations. Previous affiliations of Tatiana I. Merkulova include Novosibirsk State University.

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Brain-derived neurotrophic factor and early-life stress: Multifaceted interplay.

TL;DR: This mini-review focuses on the structure and regulation of the Bbnf gene as well as on the stress–BDNF interactions under early-life adverse conditions.
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The Effects of Chronic Stress on Brain Myelination in Humans and in Various Rodent Models

TL;DR: Recent cellular and molecular discoveries in various rodent models including models of chronic unpredictable stress, social isolation stress, chronic social defeat stress, and chronic immobilization stress are focused on.
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Molecular Adaptations to Social Defeat Stress and Induced Depression in Mice

TL;DR: The data show that the development of depression under social stress conditions is correlated with suppression of the overactive molecular response to induced stress, involving gene regulatory resistance to glucocorticoid molecules, potentially via a chromatin remodeling mechanism.
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Cytochrome P450 in fluke Opisthorchis felineus: identification and characterization.

TL;DR: The aim of this work was to identify and sequence cytochrome P450 mRNA from O. felineus and to analyze its expression at different developmental stages, indicating an important role of this biotransformation enzyme in the biochemistry of the parasite at the maritae stage.
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Regulatory SNPs: Altered Transcription Factor Binding Sites Implicated in Complex Traits and Diseases.

TL;DR: A review of the history of the discovery of regulatory SNPs can be found in this article, where the authors focus on the recent comprehensive examples of rSNPs studied from discovery of the changes in the TFBS sequence as a result of a nucleotide substitution to identification of its effect on the target gene expression and, eventually, to phenotype.