T
Tatsuya Takeshita
Researcher at Wakayama Medical University
Publications - 158
Citations - 4813
Tatsuya Takeshita is an academic researcher from Wakayama Medical University. The author has contributed to research in topics: Population & ALDH2. The author has an hindex of 36, co-authored 157 publications receiving 4543 citations. Previous affiliations of Tatsuya Takeshita include Osaka University.
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Journal ArticleDOI
Progression of chronic atrophic gastritis associated with Helicobacter pylori infection increases risk of gastric cancer
Hiroshi Ohata,Shintaro Kitauchi,Noriko Yoshimura,Kouichi Mugitani,Masataka Iwane,Hideya Nakamura,Akiyoshi Yoshikawa,Kimihiko Yanaoka,Kenji Arii,Hideyuki Tamai,Yasuhito Shimizu,Tatsuya Takeshita,Osamu Mohara,Masao Ichinose +13 more
TL;DR: It is compelling evidence that severe gastritis with extensive intestinal metaplasia is a major risk factor for gastric cancer, and they confirm the previously described model of stomach carcinogenesis: the gastritis‐metaplasia‐carcinoma sequence.
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Determination of smoking and obesity as periodontitis risks using the classification and regression tree method.
Nobuko Nishida,Muneo Tanaka,Naoji Hayashi,Hideki Nagata,Tatsuya Takeshita,Tatsuya Takeshita,Kunio Nakayama,Kanehisa Morimoto,Satoshi Shizukuishi +8 more
TL;DR: The objective of this study was to determine which lifestyle-related factors demonstrated the greater impact on periodontitis risk, and smoking displays the greatest impact among lifestyle- related factors.
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Characterization of the three genotypes of low Km aldehyde dehydrogenase in a Japanese population.
TL;DR: Findings indicate the important contribution of the ALDH2 genotype to alcohol sensitivity in Orientals and neither the manifestations nor the drinking behavior were, in general, influenced by polymorphism of the alcohol dehydrogenase β-subunit (ADH2) gene in males.
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Historical and geographical aspects of the increasing perfluorooctanoate and perfluorooctane sulfonate contamination in human serum in Japan
Kouji H. Harada,Akio Koizumi,Norimitsu Saito,Kayoko Inoue,Takeo Yoshinaga,Chigusa Date,Shigeo Fujii,Noriyuki Hachiya,Iwao Hirosawa,Shigeki Koda,Yukinori Kusaka,Katsuyuki Murata,Kazuyuki Omae,Shinichiro Shimbo,Katsunobu Takenaka,Tatsuya Takeshita,Hidemi Todoriki,Yasuhiko Wada,Takao Watanabe,Masayuki Ikeda +19 more
TL;DR: The historical samples collected from 1983 to 1999 demonstrated that the PFOA concentrations in males and females from Kyoto have increased 4.4-fold and 4.3-fold at a rate of increase of 0.49 ng/ml/year and 0.42 ng/ML/year, respectively, in contrast, serum concentrations of PFOS reached a plateau in the late 1980s.
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Cancer development based on chronic active gastritis and resulting gastric atrophy as assessed by serum levels of pepsinogen and Helicobacter pylori antibody titer.
Takeichi Yoshida,Jun Kato,Izumi Inoue,Noriko Yoshimura,Hisanobu Deguchi,Chizu Mukoubayashi,Masashi Oka,Mika Watanabe,Shotaro Enomoto,Toru Niwa,Takao Maekita,Mikitaka Iguchi,Hideyuki Tamai,Hirotoshi Utsunomiya,Nobutake Yamamichi,Mitsuhiro Fujishiro,Masataka Iwane,Tatsuya Takeshita,Toshikazu Ushijima,Masao Ichinose +19 more
TL;DR: The results clearly indicate that gastric cancer develops mainly from the gastritis‐atrophy‐metaplasia‐cancer sequence and partly from active inflammation‐based direct carcinogenesis, and that serum levels of PG and H. pylori antibody titer provide indices of cancer development in H.pylori‐infected subjects.