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Tetsuro Okabe

Researcher at University of Tokyo

Publications -  120
Citations -  3515

Tetsuro Okabe is an academic researcher from University of Tokyo. The author has contributed to research in topics: Cell culture & Growth factor. The author has an hindex of 33, co-authored 120 publications receiving 3431 citations. Previous affiliations of Tetsuro Okabe include Juntendo University.

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Demonstration of granulopoietic factor(s) in the plasma of nude mice transplanted with a human lung cancer and in the tumor tissue.

TL;DR: In this article, a human lung cancer (OTUK-tumor) was transplanted serially to nude mice, which invariably developed a marked neutrophilia, and a three to fourfold increase of colony-forming units in culture was observed in the femurs of these nude mice.
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Recombinant human granulocyte colony-stimulating factor as an activator of human granulocytes: potentiation of responses triggered by receptor- mediated agonists and stimulation of C3bi receptor expression and adherence

TL;DR: It is demonstrated that rhG-CSF can selectively stimulate mature granulocyte functions and increased the expression of C3bi receptors on human granulocytes and enhanced granulocy adherence to nylon fiber.
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Identification and characterization of receptors for granulocyte colony-stimulating factor on human placenta and trophoblastic cells

TL;DR: The presence of this receptor in these membranes suggests that human G-CSF plays some role in the feto-placental unit during human development.
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Recombinant human granulocyte colony-stimulating factor repairs the abnormalities of neutrophils in patients with myelodysplastic syndromes and chronic myelogenous leukemia.

TL;DR: The present results show that rhG-CSF is able to repair at least in part the neutrophil anomalies in patients with myelodysplastic syndromes and chronic myelogenous leukemia, and suggest the clinical usefulness of rhG -CSF for this preleukemic disorder.
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Effect of human recombinant granulocyte colony-stimulating factor on hematopoietic injury in mice induced by 5-fluorouracil.

TL;DR: Daily administration of purified human recombinant granulocyte colony-stimulating factor (rG-CSF) accelerated recovery from neutropenia in mice injured by IV administration of 5-fluorouracil.