T
Tetyana Khomenko
Researcher at University of California, Irvine
Publications - 44
Citations - 697
Tetyana Khomenko is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Cysteamine & Vascular endothelial growth factor. The author has an hindex of 17, co-authored 42 publications receiving 645 citations. Previous affiliations of Tetyana Khomenko include Veterans Health Administration & California State University, Long Beach.
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Neutralizing Anti-Vascular Endothelial Growth Factor (VEGF) Antibody Reduces Severity of Experimental Ulcerative Colitis in Rats: Direct Evidence for the Pathogenic Role of VEGF
Ganna Tolstanova,Tetyana Khomenko,Xiaoming Deng,Longchuan Chen,Andrzej S. Tarnawski,Amrita Ahluwalia,Sandor Szabo,Zsuzsanna Sandor +7 more
TL;DR: The authors showed that neutralizing anti-VEGF antibody markedly improved the clinical and morphologic features of ulcerative colitis in Sprague-Dawley rats, and the extent of macroscopic, histologic, and clinical features of colitis and colonic vascular permeability.
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Early endothelial damage and increased colonic vascular permeability in the development of experimental ulcerative colitis in rats and mice.
Ganna Tolstanova,Xiaoming Deng,Xiaoming Deng,Samuel W. French,William Lungo,Brankica Paunovic,Tetyana Khomenko,Tetyana Khomenko,Amrita Ahluwalia,Tessa M. Kaplan,Maria Dacosta-Iyer,Andrzej S. Tarnawski,Andrzej S. Tarnawski,Sandor Szabo,Sandor Szabo,Zsuzsanna Sandor,Zsuzsanna Sandor +16 more
TL;DR: This is the first demonstration in four models of UC that endothelial damage, increased colonic VP, perivascular edema, and epithelial hypoxia precede epithelial barrier dysfunction that is followed by erosions, ulceration, and inflammation in UC.
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Aging Gastropathy—Novel Mechanisms: Hypoxia, Up-regulation of Multifunctional Phosphatase PTEN, and Proapoptotic Factors
Andrzej S. Tarnawski,Rama Pai,Xiaoming Deng,Amrita Ahluwalia,Tetyana Khomenko,Tetsuya Tanigawa,Tomohiko Akahoshi,Zsuzsanna Sandor,Sandor Szabo +8 more
TL;DR: The down-regulation of PTEN in gastric mucosa of aging rats completely reversed its increased susceptibility to ethanol injury and, to determine human relevance, PTEN expression was significantly increased, whereas survivin was significantly reduced.
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Review article: transcription factors and growth factors in ulcer healing.
TL;DR: This review is focused on recent investigations demonstrating a pharmacological and patho‐physiologic role in gastroduodenal ulceration for growth factors such as basic fibroblast growth factor, platelet‐derived growth factor and vascular endothelial growth factor as well as for transcription factors.
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Measurement of sulfur-containing compounds involved in the metabolism and transport of cysteamine and cystamine. Regional differences in cerebral metabolism
John T. Pinto,Tetyana Khomenko,Tetyana Khomenko,Sandor Szabo,Sandor Szabo,Gordon D. McLaren,Gordon D. McLaren,Travis T. Denton,Boris F. Krasnikov,Thomas M. Jeitner,Arthur J.L. Cooper +10 more
TL;DR: An HPLC method with coulometric detection was used to quantitate several sulfur-containing compounds in plasma and brain following gavage feeding of cysteamine to rats, and Cysteamine, cystamine, thialysine and AECK-DD were detected in the brains of these animals.