T
Theodoros Tsakiridis
Researcher at McMaster University
Publications - 70
Citations - 4482
Theodoros Tsakiridis is an academic researcher from McMaster University. The author has contributed to research in topics: AMPK & Cancer. The author has an hindex of 29, co-authored 59 publications receiving 3690 citations. Previous affiliations of Theodoros Tsakiridis include University of Toronto & Hamilton Health Sciences.
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Journal ArticleDOI
Randomized Trial of a Hypofractionated Radiation Regimen for the Treatment of Localized Prostate Cancer
Charles Catton,Himu Lukka,Chu-Shu Gu,Jarad Martin,Stéphane Supiot,Peter Chung,Glenn Bauman,Jean-Paul Bahary,Shahida Ahmed,Patrick Cheung,Keen Hun Tai,Jackson S.Y. Wu,Matthew Parliament,Theodoros Tsakiridis,Tom Corbett,Colin Tang,Ian S. Dayes,Padraig Warde,Tim Craig,Jim A. Julian,Mark Levine +20 more
TL;DR: The hypofractionated RT regimen used in this trial was not inferior to conventional RT and was not associated with increased late toxicity, and should be considered for intermediate-risk prostate cancer.
Journal ArticleDOI
Regulation of expression of glucose transporters by glucose: a review of studies in vivo and in cell cultures.
TL;DR: In animal studies, one isoform of glucose transporters, the GLUT4 type, is down‐regulated by high levels of circulating glucose in muscle but not in fat cells, and this down‐regulation of the protein is independent of regulation of transcription.
Journal ArticleDOI
Intensity-modulated fractionated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): acute toxicity findings from an international, randomised, open-label, phase 3, non-inferiority trial.
Douglas Brand,Douglas Brand,Alison Tree,Alison Tree,Peter Ostler,Hans van der Voet,Andrew Loblaw,William Chu,Daniel Ford,Shaun Tolan,Suneil Jain,Alexander G.R. Martin,John Staffurth,Philip Camilleri,Kiran Kancherla,John Frew,Andrew K Chan,Ian S. Dayes,Daniel Henderson,Stephanie Brown,Clare Cruickshank,Stephanie Burnett,A. Duffton,Clare Griffin,Victoria Hinder,Kirsty Morrison,Kirsty Morrison,O. Naismith,Emma Hall,Nicholas van As,Nicholas van As,D Dodds,E Lartigau,S Patton,Alan J. Thompson,Mathias Winkler,P Wells,T Lymberiou,Daniel Saunders,M Vilarino-Varela,P Vavassis,Theodoros Tsakiridis,R Carlson,George Rodrigues,Jacob Tanguay,S Iqbal,Scott C. Morgan,A Mihai,A Li,O Din,Miguel Panades,R Wade,Yvonne Rimmer,J Armstrong,N Oommen +54 more
TL;DR: The results suggest that substantially shortening treatment courses with stereotactic body radiotherapy does not increase either gastrointestinal or genitourinary acute toxicity.
Journal ArticleDOI
Facilitative glucose transporters: Implications for cancer detection, prognosis and treatment.
TL;DR: GLUTs represent attractive targets for cancer therapy and this review summarizes recent studies in which GLUT1, GLUT3,GLUT5 and others are inhibited to decrease cancer growth.
Journal ArticleDOI
Metformin inhibits growth and enhances radiation response of non-small cell lung cancer (NSCLC) through ATM and AMPK
Yaryna Storozhuk,Hopmans Sn,Toran Sanli,Toran Sanli,Carly C. Barron,Evangelia Tsiani,Jean-Claude Cutz,Gregory R. Pond,James R. Wright,James R. Wright,Gurmit Singh,Gurmit Singh,Theodoros Tsakiridis,Theodoros Tsakiridis +13 more
TL;DR: The results suggest that metformin can be a clinically useful adjunct to radiotherapy in NSCLC and mediate their action through an ATM–AMPK-dependent pathway.