Nicholas van As

TL;DR: The flagship paper of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium describes the generation of the integrative analyses of 2,658 whole-cancer genomes and their matching normal tissues across 38 tumour types, the structures for international data sharing and standardized analyses, and the main scientific findings from across the consortium studies.

TL;DR: In this paper, a custom Illumina array (iCOGS) was used to genotype 211,155 SNPs in blood DNA from 25,074 prostate cancer cases and 24,272 controls from the international PRACTICAL Consortium.

TL;DR: In this paper, the authors review published work showing that SBRT offers durable local control and the potential for progression-free survival in non-liver, nonlung oligometastatic disease at a range of sites.

TL;DR: The results suggest that substantially shortening treatment courses with stereotactic body radiotherapy does not increase either gastrointestinal or genitourinary acute toxicity.

TL;DR: It is concluded that the use of stereotactic body radiotherapy for limited prostate cancer metastases with SBRT is safe and associated with a prolonged treatment progression-free survival.