T
Theresa Nguyen
Researcher at University of California, Los Angeles
Publications - 5
Citations - 363
Theresa Nguyen is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Mutant & Coenzyme Q – cytochrome c reductase. The author has an hindex of 4, co-authored 5 publications receiving 342 citations.
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Journal ArticleDOI
Use of the rpoB gene to determine the specificity of base substitution mutations on the Escherichia coli chromosome.
Lilit Garibyan,Tiffany T. Huang,Mandy Kim,Erika Wolff,Anh Nguyen,Theresa Nguyen,Amy Diep,Kaibin Hu,Ayuko Iverson,Hanjing Yang,Jeffrey H Miller +10 more
TL;DR: The results show that rpoB/Rif(r) is an accurate and easy to employ detection system, and offers the advantage of allowing analysis of mutations occurring on the chromosome rather than on an extrachromosomal element.
Journal ArticleDOI
Molecular characterization of the human COQ5 C-methyltransferase in coenzyme Q10 biosynthesis.
Theresa Nguyen,Alberto Casarin,Maria Andrea Desbats,Mara Doimo,Eva Trevisson,Carlos Santos-Ocaña,Plácido Navas,Catherine F. Clarke,Leonardo Salviati +8 more
TL;DR: The results presented suggest that human and Escherichia coli Coq5 homologs expressed in yeast retain C-methyltransferase activity but are capable of rescuing the coq5 yeast mutants only when the CoQ-synthome is assembled.
Journal ArticleDOI
Yeast Coq9 controls deamination of coenzyme Q intermediates that derive from para-aminobenzoic acid
TL;DR: Coq9 is identified as a multi-functional protein that is required for the function of Coq6 and Coq7 hydroxylases, for removal of the nitrogen substituent from pABA-derived Q intermediates, and is an essential component of the CoQ synthome.
Journal ArticleDOI
Folate status of gut microbiome affects Caenorhabditis elegans lifespan
TL;DR: It is suggested that pharmacological manipulation of the gut microbiome folate status may be a viable approach to slow animal aging, and raises questions about folate supplementation.