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Thomas A Angelovich
Researcher at Burnet Institute
Publications - 29
Citations - 1320
Thomas A Angelovich is an academic researcher from Burnet Institute. The author has contributed to research in topics: Inflammation & Monocyte. The author has an hindex of 11, co-authored 23 publications receiving 999 citations. Previous affiliations of Thomas A Angelovich include Rush University Medical Center & Monash University.
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Journal ArticleDOI
Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function
Anna C. Hearps,Anna C. Hearps,Genevieve E. Martin,Genevieve E. Martin,Thomas A Angelovich,Thomas A Angelovich,Wan-Jung Cheng,Anna Maisa,Alan L. Landay,Anthony Jaworowski,Anthony Jaworowski,Suzanne M. Crowe,Suzanne M. Crowe,Suzanne M. Crowe +13 more
TL;DR: The data show that aging is associated with chronic innate immune activation and significant changes in monocyte function, which may have implications for the development of age‐related diseases.
Journal ArticleDOI
Monocytes as Regulators of Inflammation and HIV-Related Comorbidities during cART
Joshua J. Anzinger,Tiffany R Butterfield,Thomas A Angelovich,Suzanne M. Crowe,Clovis Prince-Steve Palmer +4 more
TL;DR: The role of monocytes during cardiovascular disease, HIV-associated neurocognitive disorder, and innate immune aging are discussed and markers and sources of monocyte activation during cART-treated HIV infection are examined.
Journal ArticleDOI
HIV infection induces age-related changes to monocytes and innate immune activation in young men that persist despite combination antiretroviral therapy
Anna C. Hearps,Anna Maisa,Wan-Jung Cheng,Thomas A Angelovich,Gregor F Lichtfuss,Clovis Prince-Steve Palmer,Alan L. Landay,Anthony Jaworowski,Suzanne M. Crowe +8 more
TL;DR: HIV infection induces changes to monocyte phenotype and function in young HIV-positive males that mimic those observed in elderly uninfected individuals, suggesting HIV may accelerate age-related changes tomonocytes.
Journal ArticleDOI
Age-associated changes in monocyte and innate immune activation markers occur more rapidly in HIV infected women.
Genevieve E. Martin,Maelenn Gouillou,Anna C. Hearps,Anna C. Hearps,Thomas A Angelovich,Thomas A Angelovich,Allen C. Cheng,Allen C. Cheng,Fiona Lynch,Wan-Jung Cheng,Geza Paukovics,Clovis Prince-Steve Palmer,Clovis Prince-Steve Palmer,Richard M. Novak,Anthony Jaworowski,Anthony Jaworowski,Alan L. Landay,Suzanne M. Crowe,Suzanne M. Crowe,Suzanne M. Crowe +19 more
TL;DR: Quantifying the impact of HIV on immune aging reveals that HIV infection in women confers the equivalent of a 10–14 year increase in the levels of innate immune aging markers, which may contribute to the increased risk of inflammatory age-related diseases in HIV positive women.
Journal ArticleDOI
SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern
Anupriya Aggarwal,Anouschka Akerman,V. Milogiannakis,Mariana Ruiz Silva,Gregory J. Walker,Alberto Ospina Stella,Andrea Kindinger,Thomas A Angelovich,Emily Waring,S. Amatayakul-Chantler,Nathan J. Roth,S. Manni,Thomas Hauser,T. Barnes,Anna Condylios,Malinna Yeang,Maureen Wong,Tyra Jean,C. Foster,Daniel Christ,A. Hoppe,Mee Ling Munier,D.R. Darley,Melissa J Churchill,Damien Stark,Gail V. Matthews,William D. Rawlinson,Anthony D. Kelleher,Stuart Turville +28 more
TL;DR: In this paper , the neutralisation of Omicron BA.1, BA.2 and BA.5 was investigated using low passage clinical isolates of Clade A.2.