A
Anthony Jaworowski
Researcher at RMIT University
Publications - 90
Citations - 4348
Anthony Jaworowski is an academic researcher from RMIT University. The author has contributed to research in topics: Monocyte & Phagocytosis. The author has an hindex of 34, co-authored 88 publications receiving 3636 citations. Previous affiliations of Anthony Jaworowski include Alfred Hospital & Monash University.
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Journal ArticleDOI
Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function
Anna C. Hearps,Anna C. Hearps,Genevieve E. Martin,Genevieve E. Martin,Thomas A Angelovich,Thomas A Angelovich,Wan-Jung Cheng,Anna Maisa,Alan L. Landay,Anthony Jaworowski,Anthony Jaworowski,Suzanne M. Crowe,Suzanne M. Crowe,Suzanne M. Crowe +13 more
TL;DR: The data show that aging is associated with chronic innate immune activation and significant changes in monocyte function, which may have implications for the development of age‐related diseases.
Journal ArticleDOI
The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo.
Philip Ellery,Philip Ellery,Emma Tippett,Emma Tippett,Ya-Lin Chiu,Geza Paukovics,Paul U. Cameron,Paul U. Cameron,Ajantha Solomon,Sharon R Lewin,Sharon R Lewin,Paul R Gorry,Paul R Gorry,Anthony Jaworowski,Anthony Jaworowski,Warner C. Greene,Secondo Sonza,Secondo Sonza,Suzanne M. Crowe,Suzanne M. Crowe,Suzanne M. Crowe +20 more
TL;DR: Data show that CD16+ monocytes are preferentially susceptible to HIV-1 entry, more permissive for replication, and constitute a continuing source of viral persistence during HAART.
Journal ArticleDOI
Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton.
Paul U. Cameron,Suha Saleh,Georgina Sallmann,Ajantha Solomon,Fiona Wightman,Vanessa A. Evans,Geneviève Boucher,Elias K. Haddad,Rafick-Pierre Sekaly,Andrew N. Harman,Jenny L. Anderson,Kate L. Jones,Johnson Mak,Anthony L. Cunningham,Anthony Jaworowski,Sharon R Lewin +15 more
TL;DR: HIV-1 latency can be established in resting CD4+ T cells infected with HIV-1 after exposure to ligands for CCR7 (CCL19), CXCR3 (CXCL9 and CXCL10), and CCR6 ( CCL20) but not in unactivated CD4- T cells.
Journal ArticleDOI
Opsonic phagocytosis of Plasmodium falciparum merozoites: mechanism in human immunity and a correlate of protection against malaria
Faith H. A. Osier,Faith H. A. Osier,Gaoqian Feng,Michelle J. Boyle,Christine Langer,Jingling Zhou,Jack S. Richards,Fiona J. McCallum,Linda Reiling,Anthony Jaworowski,Robin F. Anders,Kevin Marsh,James G. Beeson,James G. Beeson +13 more
TL;DR: The opsonic phagocytosis assay appears to be a strong correlate of protection against malaria, a valuable biomarker of immunity, and provides a much-needed new tool for assessing responses to blood-stage malaria vaccines and measuring immunity in populations.
Journal ArticleDOI
The HIV Reservoir in Monocytes and Macrophages.
TL;DR: Recent developments in monocyte and macrophage biology are discussed and how this knowledge influences the evaluation of the myeloid HIV reservoir, the implications for HIV pathogenesis in both viremic and virologically-suppressed PLWH and the need to address theMyeloid reservoir in future treatment and cure strategies are discussed.