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Thomas A. DeFalco
Researcher at University of Zurich
Publications - 38
Citations - 1569
Thomas A. DeFalco is an academic researcher from University of Zurich. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 13, co-authored 23 publications receiving 946 citations. Previous affiliations of Thomas A. DeFalco include Queen's University & Sainsbury Laboratory.
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Journal ArticleDOI
Breaking the code: Ca2+ sensors in plant signalling.
TL;DR: Recent advances in research on CaMs and CMLs, CDPKs and CBLs are discussed, and the current knowledge on the different sensor classes into common physiological themes are integrated.
Journal ArticleDOI
The calcium-permeable channel OSCA1.3 regulates plant stomatal immunity.
Kathrin Thor,Shushu Jiang,Shushu Jiang,Erwan Michard,Jeoffrey George,Jeoffrey George,Sönke Scherzer,Shouguang Huang,Julian Dindas,Paul Derbyshire,Nuno Leitão,Thomas A. DeFalco,Thomas A. DeFalco,Philipp Köster,Kerri Hunter,Sachie Kimura,Sachie Kimura,Julien Gronnier,Julien Gronnier,Lena Stransfeld,Lena Stransfeld,Yasuhiro Kadota,Christoph A. Bücherl,Myriam Charpentier,Michael Wrzaczek,Dan MacLean,Giles E. D. Oldroyd,Giles E. D. Oldroyd,Frank L.H. Menke,M. Rob G. Roelfsema,Rainer Hedrich,José A. Feijó,Cyril Zipfel,Cyril Zipfel +33 more
TL;DR: It is reported that the Arabidopsis thaliana Ca 2+ -permeable channel OSCA1.3 controls stomatal closure during immune signalling and suggests specificity in Ca 2- influx mechanisms in response to different stresses.
Journal ArticleDOI
Mechanisms of RALF peptide perception by a heterotypic receptor complex
Yu Xiao,Martin Stegmann,Martin Stegmann,Zhifu Han,Thomas A. DeFalco,Thomas A. DeFalco,Katarzyna Parys,Li Xu,Youssef Belkhadir,Cyril Zipfel,Cyril Zipfel,Jijie Chai,Jijie Chai,Jijie Chai +13 more
TL;DR: This work reveals a mechanism of peptide perception in plants by GPI-anchored proteins that act together with a phylogenetically unrelated receptor kinase FER and the LLG1 protein in Arabidopsis thaliana, suggesting a role for diverse RALF peptides in regulating multiple growth and reproductive processes in plants.
Journal ArticleDOI
Molecular mechanisms of early plant pattern-triggered immune signaling.
TL;DR: In this article, the critical roles of pattern recognition receptors (PRRs) complex formation and phosphorylation in activating pattern-triggered immunity (PTI) signaling, as well as the emerging paradigm in which receptor-like cytoplasmic kinases (RLCKs) act as executors of signaling downstream of PRR activation.
Journal ArticleDOI
Phosphocode-dependent functional dichotomy of a common co-receptor in plant signalling
Artemis Perraki,Artemis Perraki,Thomas A. DeFalco,Thomas A. DeFalco,Paul Derbyshire,Julian Avila,Julian Avila,David Séré,David Séré,Jan Sklenar,Xingyun Qi,Lena Stransfeld,Lena Stransfeld,Benjamin Schwessinger,Benjamin Schwessinger,Yasuhiro Kadota,Alberto P. Macho,Alberto P. Macho,Shushu Jiang,Shushu Jiang,Daniel Couto,Daniel Couto,Keiko U. Torii,Frank L.H. Menke,Cyril Zipfel,Cyril Zipfel +25 more
TL;DR: The results suggest a phosphocode-based dichotomy of BAK1 function in plant signalling, and provide insights into receptor kinase activation that have broad implications for the understanding of how plants respond to their changing environment.