T
Thomas Braunbeck
Researcher at Heidelberg University
Publications - 223
Citations - 11361
Thomas Braunbeck is an academic researcher from Heidelberg University. The author has contributed to research in topics: Zebrafish & Genotoxicity. The author has an hindex of 57, co-authored 211 publications receiving 9676 citations.
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Zebrafish embryos as an alternative to animal experiments--a commentary on the definition of the onset of protected life stages in animal welfare regulations.
Uwe Strähle,Stefan Scholz,Robert Geisler,Petra Greiner,Henner Hollert,Sepand Rastegar,Axel Schumacher,Ingrid W.T. Selderslaghs,Carsten Weiss,Hilda Witters,Thomas Braunbeck +10 more
TL;DR: It is concluded that zebrafish larvae can indeed be regarded as independently feeding from 120 h after fertilization, and should thus be subject to regulations for animal experiments from 120H after fertilized onwards.
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Transfer of benzo[a]pyrene from microplastics to Artemia nauplii and further to zebrafish via a trophic food web experiment: CYP1A induction and visual tracking of persistent organic pollutants.
TL;DR: Fluorescence tracking of benzo[a]pyrene indicates that food‐borne microplastic‐associated POPs may actually desorb in the intestine of fish and are thus transferred to the intestinal epithelium and liver.
Journal Article
Towards an alternative for the acute fish LC(50) test in chemical assessment: the fish embryo toxicity test goes multi-species -- an update.
Thomas Braunbeck,Melanie Boettcher,Henner Hollert,Thomas Kosmehl,Eva Lammer,Erik Leist,Mark Rudolf,Nadja Seitz +7 more
TL;DR: Results document that the transfer of the protocol is possible with only minor modifications and examples are given as to how additional endpoints can be incorporated into the fish embryo test protocol to extend its scope, e.g. to sediment toxicity assessment or genotoxicity and mutagenicity testing.
Journal ArticleDOI
The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research.
Michelle R. Embry,Scott E. Belanger,Thomas Braunbeck,Malyka Galay-Burgos,Marlies Halder,David E. Hinton,Marc Léonard,Adam Lillicrap,Teresa J. Norberg-King,Graham Whale +9 more
TL;DR: The goal was to review the state of the science regarding the investigation of fish embryonic tests, pain and distress in fish, emerging approaches utilizing fish embryos, and the use of fish embryo toxicity test data in various types of environmental assessments.
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Relevance of nano- and microplastics for freshwater ecosystems: A critical review
Rita Triebskorn,Thomas Braunbeck,Tamara Grummt,Lisa Hanslik,Sven Huppertsberg,Martin Jekel,Thomas P. Knepper,Stefanie Krais,Yanina K. Müller,Marco Pittroff,Aki Sebastian Ruhl,Aki Sebastian Ruhl,Hannah Schmieg,Christoph Schür,Claudia Strobel,Martin Wagner,Nicole Zumbülte,Heinz-R. Köhler +17 more
TL;DR: In this article, the authors reviewed the state-of-the-science on microplastics types and particle concentrations in freshwater ecosystems, MP and nanoplastics uptake and tissue translocation, MP/NP-induced effects in freshwater organisms, and capabilities of MP and NP to modulate the toxicity of environmental chemicals.