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Thomas Cherian

Researcher at World Health Organization

Publications -  125
Citations -  7732

Thomas Cherian is an academic researcher from World Health Organization. The author has contributed to research in topics: Vaccination & Medicine. The author has an hindex of 35, co-authored 108 publications receiving 6957 citations. Previous affiliations of Thomas Cherian include Christian Medical College & Hospital & Indian Council of Medical Research.

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Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates

TL;DR: The burden of pneumococcal pneumonia is measured by applying the proportion of pneumonia cases caused by S pneumoniae derived from efficacy estimates from vaccine trials to WHO country-specific estimates of all-cause pneumonia cases and deaths, using disease incidence and case-fatality data from a systematic literature review.
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Burden of disease caused by Haemophilus influenzae type b in children younger than 5 years: global estimates.

TL;DR: Global burden of Hib disease is substantial and almost entirely vaccine preventable, and expanded use of Hib vaccine could reduce childhood pneumonia and meningitis, and decrease child mortality.
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Serotype-specific changes in invasive pneumococcal disease after pneumococcal conjugate vaccine introduction: a pooled analysis of multiple surveillance sites.

TL;DR: In a pooled analysis of data collected from invasive pneumococcal disease surveillance databases, Daniel Feikin and colleagues examine serotype replacement after the introduction of 7-valent pneumococCal conjugate vaccine (PCV7) into national immunization programs.
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Serological criteria for evaluation and licensure of new pneumococcal conjugate vaccine formulations for use in infants.

TL;DR: This report analyses the various options with their relative merits and drawbacks and provides preliminary recommendations as guidance to regulatory agencies in evaluating these vaccines for the purposes of licensure.