T
Thomas J. Cahill
Researcher at University of Oxford
Publications - 54
Citations - 5434
Thomas J. Cahill is an academic researcher from University of Oxford. The author has contributed to research in topics: Infective endocarditis & Medicine. The author has an hindex of 16, co-authored 47 publications receiving 1804 citations. Previous affiliations of Thomas J. Cahill include University College London & Wellcome Trust Centre for Human Genetics.
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Journal ArticleDOI
The cardiac lymphatic system stimulates resolution of inflammation following myocardial infarction
Joaquim M. Vieira,Sophie Norman,Cristina Villa del Campo,Thomas J. Cahill,Damien N. Barnette,Mala Gunadasa-Rohling,Louise A. Johnson,David R. Greaves,Carolyn A. Carr,David A. Jackson,Paul R. Riley +10 more
TL;DR: It is revealed that stimulation of cardiac lymphangiogenesis with VEGF-C improves clearance of the acute inflammatory response after MI by trafficking immune cells to draining mediastinal lymph nodes (MLNs) in a process dependent on lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1).
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Heart failure after myocardial infarction in the era of primary percutaneous coronary intervention: Mechanisms, incidence and identification of patients at risk.
TL;DR: Current and emerging strategies for early detection of patients at risk of HF after MI, with a view to identification of patient cohorts for novel therapeutic agents are reviewed.
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Genetic Cardiomyopathies Causing Heart Failure
TL;DR: This review concludes that efforts to unravel the basis of the familial cardiomyopathies at the mendelian end of the spectrum already have begun to deliver on the promise of informative mechanisms, novel gene-based diagnostics, and therapies for distinct subtypes of HF.
Journal ArticleDOI
Transcatheter aortic valve implantation: current status and future perspectives.
Thomas J. Cahill,Mao Chen,Kentaro Hayashida,Azeem Latib,Thomas Modine,Nicolo Piazza,Simon Redwood,Lars Søndergaard,Bernard Prendergast +8 more
TL;DR: In the 16 years since the first pioneering procedure, transcatheter aortic valve implantation (TAVI) has come of age and become a routine strategy for valve replacement, increasingly performed under conscious sedation via transfemoral access.
Journal ArticleDOI
X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3
Chiara Olcese,Chiara Olcese,Mitali P. Patel,Amelia Shoemark,Santeri Kiviluoto,Marie Legendre,Hywel Williams,Cara K. Vaughan,Jane Hayward,Alice Goldenberg,Richard D. Emes,Mustafa M. Munye,Laura Dyer,Thomas J. Cahill,Jeremy Bevillard,Corinne Gehrig,Michel Guipponi,Michel Guipponi,Sandra Chantot,Philippe Duquesnoy,Lucie Thomas,Ludovic Jeanson,Bruno Copin,Aline Tamalet,Christel Thauvin-Robinet,Jean Francois Papon,Antoine Garin,Isabelle Pin,Gabriella Vera,Paul Aurora,Paul Aurora,Mahmoud R. Fassad,Mahmoud R. Fassad,Lucy Jenkins,Christopher Boustred,Thomas Cullup,Mellisa Dixon,Alexandros Onoufriadis,Andrew Bush,Eddie M.K. Chung,Stylianos E. Antonarakis,Stylianos E. Antonarakis,Michael R. Loebinger,Robert Wilson,Miguel Armengot,Estelle Escudier,Claire Hogg,Serge Amselem,Zhaoxia Sun,Lucia Bartoloni,Jean-Louis Blouin,Jean-Louis Blouin,Hannah M. Mitchison +52 more
TL;DR: It is proposed that PIH1D3, a protein that emerges as a new player of the cytoplasmic pre-assembly pathway, is part of a complementary conserved R2TP-like HSP90 co-chaperone complex, the loss of which affects assembly of a subset of inner arm dyneins.