T
Thomas W. Jeffries
Researcher at University of Wisconsin-Madison
Publications - 164
Citations - 12514
Thomas W. Jeffries is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Xylose & Fermentation. The author has an hindex of 65, co-authored 164 publications receiving 11876 citations. Previous affiliations of Thomas W. Jeffries include Great Lakes Institute of Management & Rutgers University.
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Bacteria engineered for fuel ethanol production: current status.
TL;DR: The lack of industrially suitable microorganisms for converting biomass into fuel ethanol has traditionally been cited as a major technical roadblock to developing a bioethanol industry, but in the last two decades, numerous microorganisms have been engineered to selectively produce ethanol.
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Metabolic engineering for improved fermentation of pentoses by yeasts
Thomas W. Jeffries,Yong Su Jin +1 more
TL;DR: Researchers have engineered xylose metabolism in S. cerevisiae, showing that adapted strains of Pichia stipitis have been shown to ferment hydrolysates with ethanol yields of 0.45 g g−1 sugar consumed, so commercialization seems feasible for some applications.
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Genome sequence of the lignocellulose-bioconverting and xylose-fermenting yeast Pichia stipitis
Thomas W. Jeffries,Thomas W. Jeffries,Igor V. Grigoriev,Jane Grimwood,Jose M. Laplaza,Andrea Aerts,Asaf Salamov,Jeremy Schmutz,Erika Lindquist,Paramvir S. Dehal,Harris Shapiro,Yong Su Jin,Volkmar Passoth,Paul G. Richardson +13 more
TL;DR: The genome sequence provides insight into how P. stipitis regulates its redox balance while very efficiently fermenting xylose under microaerobic conditions.
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Engineering yeasts for xylose metabolism.
TL;DR: The recent determination of the genome sequence for P. stipitis is important, as its genome characteristics and regulatory patterns could serve as guides for further development in this natural xylose-fermenting yeast or in engineered Saccharomyces cerevisiae.
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Nutritional Regulation of Lignin Degradation by Phanerochaete chrysosporium.
TL;DR: In carbohydrate-limited cultures, ligninolytic activity appeared when the supplied carbohydrate was depleted, and this activity was associated with a decrease in mycelial dry weight, and the balance of trace metals, Mg, and Ca was important for lignin degradation.