Institution
The Wallace H. Coulter Department of Biomedical Engineering
Education•Atlanta, Georgia, United States•
About: The Wallace H. Coulter Department of Biomedical Engineering is a education organization based out in Atlanta, Georgia, United States. It is known for research contribution in the topics: Nanocages & Stem cell. The organization has 609 authors who have published 948 publications receiving 49428 citations. The organization is also known as: Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University.
Papers published on a yearly basis
Papers
More filters
••
TL;DR: This work aims to provide a comprehensive overview of electrospun nanofibers, including the principle, methods, materials, and applications, and highlights the most relevant and recent advances related to the applications by focusing on the most representative examples.
Abstract: Electrospinning is a versatile and viable technique for generating ultrathin fibers. Remarkable progress has been made with regard to the development of electrospinning methods and engineering of electrospun nanofibers to suit or enable various applications. We aim to provide a comprehensive overview of electrospinning, including the principle, methods, materials, and applications. We begin with a brief introduction to the early history of electrospinning, followed by discussion of its principle and typical apparatus. We then discuss its renaissance over the past two decades as a powerful technology for the production of nanofibers with diversified compositions, structures, and properties. Afterward, we discuss the applications of electrospun nanofibers, including their use as "smart" mats, filtration membranes, catalytic supports, energy harvesting/conversion/storage components, and photonic and electronic devices, as well as biomedical scaffolds. We highlight the most relevant and recent advances related to the applications of electrospun nanofibers by focusing on the most representative examples. We also offer perspectives on the challenges, opportunities, and new directions for future development. At the end, we discuss approaches to the scale-up production of electrospun nanofibers and briefly discuss various types of commercial products based on electrospun nanofibers that have found widespread use in our everyday life.
2,289 citations
••
TL;DR: An overview of the literature on medical hyperspectral imaging technology and its applications is presented, an introduction for those new to the field, an overview for those working in the field and a reference for those searching for literature on a specific application are presented.
Abstract: Hyperspectral imaging (HSI) is an emerging imaging modality for medical applications, especially in disease diagnosis and image-guided surgery. HSI acquires a three-dimensional dataset called hypercube, with two spatial dimensions and one spectral dimension. Spatially resolved spectral imaging obtained by HSI provides diagnostic information about the tissue physiology, morphology, and composition. This review paper presents an overview of the literature on medical hyperspectral imaging technology and its applications. The aim of the survey is threefold: an introduction for those new to the field, an overview for those working in the field, and a reference for those searching for literature on a specific application.
1,605 citations
••
TL;DR: It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
Abstract: In medicine, nanotechnology has sparked a rapidly growing interest as it promises to solve a number of issues associated with conventional therapeutic agents, including their poor water solubility (at least, for most anticancer drugs), lack of targeting capability, nonspecific distribution, systemic toxicity, and low therapeutic index. Over the past several decades, remarkable progress has been made in the development and application of engineered nanoparticles to treat cancer more effectively. For example, therapeutic agents have been integrated with nanoparticles engineered with optimal sizes, shapes, and surface properties to increase their solubility, prolong their circulation half-life, improve their biodistribution, and reduce their immunogenicity. Nanoparticles and their payloads have also been favorably delivered into tumors by taking advantage of the pathophysiological conditions, such as the enhanced permeability and retention effect, and the spatial variations in the pH value. Additionally, targeting ligands (e.g., small organic molecules, peptides, antibodies, and nucleic acids) have been added to the surface of nanoparticles to specifically target cancerous cells through selective binding to the receptors overexpressed on their surface. Furthermore, it has been demonstrated that multiple types of therapeutic drugs and/or diagnostic agents (e.g., contrast agents) could be delivered through the same carrier to enable combination therapy with a potential to overcome multidrug resistance, and real-time readout on the treatment efficacy. It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
1,603 citations
••
TL;DR: A comprehensive review of recent research activities on bimetallic nanocrystals, featuring key examples from the literature that exemplify critical concepts and place a special emphasis on mechanistic understanding.
Abstract: Achieving mastery over the synthesis of metal nanocrystals has emerged as one of the foremost scientific endeavors in recent years. This intense interest stems from the fact that the composition, size, and shape of nanocrystals not only define their overall physicochemical properties but also determine their effectiveness in technologically important applications. Our aim is to present a comprehensive review of recent research activities on bimetallic nanocrystals. We begin with a brief introduction to the architectural diversity of bimetallic nanocrystals, followed by discussion of the various synthetic techniques necessary for controlling the elemental ratio and spatial arrangement. We have selected key examples from the literature that exemplify critical concepts and place a special emphasis on mechanistic understanding. We then discuss the composition-dependent properties of bimetallic nanocrystals in terms of catalysis, optics, and magnetism and conclude the Review by highlighting applications that h...
1,203 citations
••
TL;DR: Seven general categories of interaction techniques widely used in Infovis are proposed, organized around a user's intent while interacting with a system rather than the low-level interaction techniques provided by a system.
Abstract: Even though interaction is an important part of information visualization (Infovis), it has garnered a relatively low level of attention from the Infovis community. A few frameworks and taxonomies of Infovis interaction techniques exist, but they typically focus on low-level operations and do not address the variety of benefits interaction provides. After conducting an extensive review of Infovis systems and their interactive capabilities, we propose seven general categories of interaction techniques widely used in Infovis: 1) Select, 2) Explore, 3) Reconfigure, 4) Encode, 5) Abstract/Elaborate, 6) Filter, and 7) Connect. These categories are organized around a user's intent while interacting with a system rather than the low-level interaction techniques provided by a system. The categories can act as a framework to help discuss and evaluate interaction techniques and hopefully lay an initial foundation toward a deeper understanding and a science of interaction.
1,018 citations
Authors
Showing all 629 results
Name | H-index | Papers | Citations |
---|---|---|---|
Younan Xia | 216 | 943 | 175757 |
David G. Harrison | 137 | 492 | 72190 |
Michael Davis | 129 | 566 | 61920 |
Qian Wang | 108 | 2148 | 65557 |
Mark R. Prausnitz | 97 | 392 | 37538 |
Shuming Nie | 95 | 286 | 64937 |
Sandeep Kumar | 94 | 1563 | 38652 |
Xiaoping Hu | 85 | 450 | 24291 |
Wei Sun | 78 | 770 | 24297 |
Robert E. Gross | 77 | 465 | 22825 |
Shuichi Takayama | 77 | 361 | 23775 |
Ajit P. Yoganathan | 74 | 626 | 21612 |
Stanislav Emelianov | 69 | 382 | 17893 |
Jie Zeng | 68 | 218 | 16715 |
Hanjoong Jo | 67 | 208 | 14250 |