T
Timo Strünker
Researcher at University of Münster
Publications - 49
Citations - 2574
Timo Strünker is an academic researcher from University of Münster. The author has contributed to research in topics: Sperm & Sperm motility. The author has an hindex of 20, co-authored 42 publications receiving 2134 citations. Previous affiliations of Timo Strünker include Max Planck Society & Forschungszentrum Jülich.
Papers
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Journal ArticleDOI
An Assay to Determine Mechanisms of Rapid Autoantibody-Induced Neurotransmitter Receptor Endocytosis and Vesicular Trafficking in Autoimmune Encephalitis.
Elsie Amedonu,Christoph Brenker,Sumanta Barman,Julian A. Schreiber,Sebastian Becker,Stefan Peischard,Nathalie Strutz-Seebohm,Christine Strippel,Andre Dik,Hans-Peter Hartung,Thomas Budde,Heinz Wiendl,Timo Strünker,Bernhard Wünsch,Norbert Goebels,Sven G. Meuth,Guiscard Seebohm,Nico Melzer +17 more
TL;DR: A role for PSD-95 in stabilization of NMDARs in the cell membrane in the presence of GluN1-aAbpH−rhod is demonstrated, while RAB proteins did not exert a significant effect on vertical trafficking of the internalized NMDar autoantibody complex in this heterologous expression system.
Journal ArticleDOI
HPLC fluorescence assay for measuring the activity of diacylglycerol lipases and the action of inhibitors thereof.
TL;DR: In this paper , a pyrene-labeled 1,2-diacylglycerol substrate was used to evaluate the action of several known DAGL inhibitors, and the method was verified by measuring the IC50 values for a subset of inhibitors by HPLC and single-quad MS detection.
Journal ArticleDOI
A Receptor Guanylyl Cyclase Reveals Auto-Phosphatase Activity
Magdalena Sznapka,Timo Strünker,Reinhard Seifert,Normann Goodwin,Nachiket D. Kashikar,U. Benjamin Kaupp +5 more
TL;DR: It is concluded that the occupied GC inactivates by auto-dephosporylation (fast phase) and additionally can dephosphorylate adjacent non-occupied GCs (slow phase), and it is shown for the first time that a receptor GC is regulated byAuto-Dephosphorylation.
Peer ReviewDOI
Author response: A novel biosensor to study cAMP dynamics in cilia and flagella
Shatanik Mukherjee,Vera Jansen,Jan F. Jikeli,Hussein Hamzeh,Luis Alvarez,Marco Dombrowski,Melanie Balbach,Timo Strünker,Reinhard Seifert,U. Benjamin Kaupp,Dagmar Wachten +10 more
Journal ArticleDOI
Synthesis and Functional Characterization of Novel RU1968-Derived CatSper Inhibitors with Reduced Stereochemical Complexity.
Tobias Schierling,Beatrice Tosi,Clara Eisenhardt,Sophie Reining,Constantin G. Daniliuc,Christoph Brenker,Timo Strünker,Bernhard Wünsch +7 more
TL;DR: In this article , the synthesis of enantiomerically pure aminomethyl RU1968 analogues without the C-21 CH3 moiety has been studied and compared to RU1968 with similar and even twofold enhanced potency.