T
Timothy H. Moran
Researcher at Johns Hopkins University School of Medicine
Publications - 373
Citations - 22541
Timothy H. Moran is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Cholecystokinin & Gastric emptying. The author has an hindex of 77, co-authored 363 publications receiving 21338 citations. Previous affiliations of Timothy H. Moran include Bar-Ilan University & Xi'an Jiaotong University.
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Journal ArticleDOI
A mouse model for Down syndrome exhibits learning and behaviour deficits
Roger H. Reeves,N.G. Irving,Timothy H. Moran,Anny Wohn,Cheryl A. Kitt,Sangram S. Sisodia,Cecilia Schmidt,Roderick T. Bronson,Muriel T. Davisson +8 more
TL;DR: In this article, the reproducibility of this phenotype among mice with segmental trisomy 16 (Ts65Dn mice) indicates that dosage imbalance for a gene or genes in this region contributes to this impairment.
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Neurobiology of exercise.
Rod K. Dishman,Hans-Rudolf Berthoud,Frank W. Booth,Carl W. Cotman,V. Reggie Edgerton,Monika Fleshner,Simon C. Gandevia,Fernando Gomez-Pinilla,Benjamin N. Greenwood,Charles H. Hillman,Arthur F. Kramer,Barry E. Levin,Timothy H. Moran,Amelia A. Russo-Neustadt,John D. Salamone,Jacqueline D. Van Hoomissen,Charles E. Wade,David A. York,Michael J. Zigmond +18 more
TL;DR: Mechanisms explaining these adaptations are not as yet known, but metabolic and neurochemical pathways among skeletal muscle, the spinal cord, and the brain offer plausible, testable mechanisms that might help explain effects of physical activity and exercise on the central nervous system.
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Two brain cholecystokinin receptors: implications for behavioral actions.
TL;DR: The distribution and relative specificity of cholecystokinin receptors in the rat brain was mapped by in vitro autoradiography with [125I]CCK-33 and two distinct binding patterns were identified, suggesting two CCK receptor types.
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p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease.
Byoung-Il Bae,Hong Xu,Shuichi Igarashi,Masahiro Fujimuro,Nishant Agrawal,Yoichi Taya,S. Diane Hayward,Timothy H. Moran,Craig Montell,Christopher A. Ross,Solomon H. Snyder,Akira Sawa +11 more
TL;DR: Evidence for a specific role of p53 in the mitochondria-associated cellular dysfunction and behavioral abnormalities of Huntington's disease is presented and findings suggest that p53 links nuclear and mitochondrial pathologies characteristic of HD.
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Excessive sugar intake alters binding to dopamine and mu-opioid receptors in the brain
Carlo Colantuoni,J. Schwenker,J. McCarthy,Pedro Rada,Bruce Ladenheim,Jean Lud Cadet,Gary J. Schwartz,Timothy H. Moran,Bartley G. Hoebel +8 more
TL;DR: In intermittent, excessive sugar intake sensitized D-1 and mu-1 receptors much like some drugs of abuse, stimulating neural systems implicated in drug dependence.