T
Tingting Wu
Researcher at University of Chicago
Publications - 9
Citations - 807
Tingting Wu is an academic researcher from University of Chicago. The author has contributed to research in topics: Mesenchymal stem cell & Progenitor cell. The author has an hindex of 7, co-authored 7 publications receiving 332 citations. Previous affiliations of Tingting Wu include Chongqing University & Wuhan University.
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Journal ArticleDOI
Notch Signaling Augments BMP9-Induced Bone Formation by Promoting the Osteogenesis-Angiogenesis Coupling Process in Mesenchymal Stem Cells (MSCs).
Junyi Liao,Qiang Wei,Yulong Zou,Jiaming Fan,Dongzhe Song,Jing Cui,Wenwen Zhang,Yunxiao Zhu,Chao Ma,Xue Hu,Xiangyang Qu,Liqun Chen,Xinyi Yu,Zhicai Zhang,Claire Q.F. Wang,Chen Zhao,Zongyue Zeng,Ruyi Zhang,Shujuan Yan,Tingting Wu,Xingye Wu,Yi Shu,Jiayan Lei,Yasha Li,Hue H. Luu,Michael J. Lee,Russell R. Reid,Guillermo A. Ameer,Jennifer Moriatis Wolf,Tong-Chuan He,Wei Huang +30 more
TL;DR: It’s conceivable that simultaneous activation of the BMP9 and Notch pathways should efficiently couple osteogenesis and angiogenesis of MSCs for successful bone tissue engineering.
Journal ArticleDOI
lncRNA H19 mediates BMP9-induced osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling
Junyi Liao,Junyi Liao,Xinyi Yu,Xinyi Yu,Xue Hu,Xue Hu,Jiaming Fan,Jiaming Fan,Jing Wang,Jing Wang,Zhicai Zhang,Zhicai Zhang,Chen Zhao,Chen Zhao,Zongyue Zeng,Zongyue Zeng,Yi Shu,Yi Shu,Ruyi Zhang,Ruyi Zhang,Shujuan Yan,Shujuan Yan,Yasha Li,Yasha Li,Wenwen Zhang,Wenwen Zhang,Jing Cui,Jing Cui,Chao Ma,Chao Ma,Li Li,Li Li,Yichun Yu,Yichun Yu,Tingting Wu,Tingting Wu,Xingye Wu,Xingye Wu,Jiayan Lei,Jiayan Lei,Jia Wang,Jia Wang,Chao Yang,Chao Yang,Ke Wu,Ke Wu,Ying Wu,Ying Wu,Jun Tang,Bai-Cheng He,Bai-Cheng He,Zhong-Liang Deng,Zhong-Liang Deng,Hue H. Luu,Rex C. Haydon,Russell R. Reid,Michael J. Lee,Jennifer Moriatis Wolf,Wei Huang,Tong-Chuan He,Tong-Chuan He +60 more
TL;DR: The findings suggest that the well-coordinated biphasic expression of lncRNA H19 may be essential in BMP9-induced osteogenic differentiation of MSCs, and that dysregulated H19 expression may impair normal osteogenesis, leading to pathogenic processes, such as bone tumor development.
Journal ArticleDOI
Noncanonical Wnt signaling plays an important role in modulating canonical Wnt-regulated stemness, proliferation and terminal differentiation of hepatic progenitors
Jiaming Fan,Qiang Wei,Junyi Liao,Junyi Liao,Yulong Zou,Yulong Zou,Dongzhe Song,Dongzhe Song,Dongmei Xiong,Chao Ma,Chao Ma,Xue Hu,Xue Hu,Xiangyang Qu,Xiangyang Qu,Liqun Chen,Liqun Chen,Li Li,Li Li,Yichun Yu,Yichun Yu,Xinyi Yu,Xinyi Yu,Zhicai Zhang,Zhicai Zhang,Chen Zhao,Chen Zhao,Zongyue Zeng,Zongyue Zeng,Ruyi Zhang,Ruyi Zhang,Shujuan Yan,Shujuan Yan,Tingting Wu,Tingting Wu,Xingye Wu,Xingye Wu,Yi Shu,Yi Shu,Jiayan Lei,Jiayan Lei,Yasha Li,Yasha Li,Wenwen Zhang,Wenwen Zhang,Rex C. Haydon,Hue H. Luu,Ailong Huang,Tong-Chuan He,Hua Tang +49 more
TL;DR: The results strongly suggest that noncanonical Wnts may play an important role in fine-tuning Wnt/β-catenin functions during liver development and liver regeneration and/or progenitor cell-based therapies for liver diseases.
Journal ArticleDOI
Anthelmintic mebendazole enhances cisplatin’s effect on suppressing cell proliferation and promotes differentiation of head and neck squamous cell carcinoma (HNSCC)
Fugui Zhang,Yong Li,Hongmei Zhang,Hongmei Zhang,Enyi Huang,Enyi Huang,Lina Gao,Wenping Luo,Wenping Luo,Qiang Wei,Jiaming Fan,Jiaming Fan,Dongzhe Song,Dongzhe Song,Junyi Liao,Junyi Liao,Yulong Zou,Yulong Zou,Feng Liu,Feng Liu,Jianxiang Liu,Jianxiang Liu,Jiayi Huang,Jiayi Huang,Dan Guo,Dan Guo,Chao Ma,Chao Ma,Xue Hu,Xue Hu,Li Li,Li Li,Xiangyang Qu,Xiangyang Qu,Liqun Chen,Liqun Chen,Xinyi Yu,Xinyi Yu,Zhicai Zhang,Zhicai Zhang,Tingting Wu,Tingting Wu,Hue H. Luu,Rex C. Haydon,Jinlin Song,Tong-Chuan He,Tong-Chuan He,Ping Ji +47 more
TL;DR: The results are the first to demonstrate that MBZ may exert its anticancer activity by inhibiting proliferation while promoting differentiation of certain HNSCC cancer cells.
Journal ArticleDOI
Monensin inhibits cell proliferation and tumor growth of chemo-resistant pancreatic cancer cells by targeting the EGFR signaling pathway
Xin Wang,Xin Wang,Xingye Wu,Xingye Wu,Zhonglin Zhang,Zhonglin Zhang,Chao Ma,Chao Ma,Tingting Wu,Tingting Wu,Shengli Tang,Shengli Tang,Zongyue Zeng,Zongyue Zeng,Shifeng Huang,Shifeng Huang,Cheng Gong,Cheng Gong,Chengfu Yuan,Chengfu Yuan,Linghuan Zhang,Linghuan Zhang,Yixiao Feng,Yixiao Feng,Bo Huang,Bo Huang,Bo Huang,Wei Liu,Wei Liu,Bo Zhang,Bo Zhang,Yi Shen,Yi Shen,Wenping Luo,Wenping Luo,Xi Wang,Xi Wang,Bo Liu,Bo Liu,Yan Lei,Yan Lei,Zhenyu Ye,Zhenyu Ye,Ling Zhao,Ling Zhao,Daigui Cao,Daigui Cao,Lijuan Yang,Lijuan Yang,Xian Chen,Xian Chen,Rex C. Haydon,Hue H. Luu,Bing Peng,Xubao Liu,Tong-Chuan He +55 more
TL;DR: The findings demonstrate that monensin can be repurposed as an effective anti-pancreatic cancer drug even though more investigations are needed to validate its safety and anticancer efficacy in pre-clinical and clinical models.