T
Tirayut Vilaivan
Researcher at Chulalongkorn University
Publications - 165
Citations - 4478
Tirayut Vilaivan is an academic researcher from Chulalongkorn University. The author has contributed to research in topics: Peptide nucleic acid & Nucleic acid. The author has an hindex of 34, co-authored 153 publications receiving 3799 citations. Previous affiliations of Tirayut Vilaivan include Osaka City University & University of Oxford.
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Journal ArticleDOI
Multiplex Paper-Based Colorimetric DNA Sensor Using Pyrrolidinyl Peptide Nucleic Acid-Induced AgNPs Aggregation for Detecting MERS-CoV, MTB, and HPV Oligonucleotides
Prinjaporn Teengam,Weena Siangproh,Adisorn Tuantranont,Tirayut Vilaivan,Orawon Chailapakul,Charles S. Henry +5 more
TL;DR: A paper-based colorimetric assay for DNA detection based on pyrrolidinyl peptide nucleic acid (acpcPNA)-induced nanoparticle aggregation is reported as an alternative to traditional colorimetry approaches.
Journal ArticleDOI
Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target
Yongyuth Yuthavong,Bongkoch Tarnchompoo,Tirayut Vilaivan,Penchit Chitnumsub,Sumalee Kamchonwongpaisan,Susan A. Charman,Danielle N McLennan,Karen L. White,Livia Vivas,Emily Bongard,Chawanee Thongphanchang,Supannee Taweechai,Jarunee Vanichtanankul,Roonglawan Rattanajak,Uthai Arwon,Pascal Fantauzzi,Jirundon Yuvaniyama,William N. Charman,David Matthews +18 more
TL;DR: The use of cocrystal structures with inhibitors and substrates, along with efficacy and pharmacokinetic profiling for the design, characterization, and preclinical development of a selective, highly efficacious, and orally available antimalarial drug candidate that potently inhibits both wild-type and clinically relevant mutated forms of Plasmodium falciparum (Pf) DHFR.
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Electrochemical paper-based peptide nucleic acid biosensor for detecting human papillomavirus.
Prinjaporn Teengam,Weena Siangproh,Adisorn Tuantranont,Charles S. Henry,Tirayut Vilaivan,Orawon Chailapakul +5 more
TL;DR: A novel paper-based electrochemical biosensor using an anthraquinone-labeled pyrrolidinyl peptide nucleic acid probe (AQ-PNA) probe and graphene-polyaniline modified electrode to detect human papillomavirus (HPV) type 16 is promising for the screening and monitoring of the amount of HPV-DNA type 16 to identify the primary stages of cervical cancer.
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Organocatalyzed asymmetric alpha-oxidation, alpha-aminoxylation and alpha-amination of carbonyl compounds.
TL;DR: In this paper, a review of catalysts, reactions and catalysts for asymmetric alpha-heteroatom functionalization of aldehydes, ketones and related active methylene compounds is presented.