T
Tobias Pfaller
Researcher at University of Salzburg
Publications - 9
Citations - 1928
Tobias Pfaller is an academic researcher from University of Salzburg. The author has contributed to research in topics: Protein Corona & Surface charge. The author has an hindex of 7, co-authored 9 publications receiving 1727 citations.
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Journal ArticleDOI
Time Evolution of the Nanoparticle Protein Corona
TL;DR: An evolution from a loosely attached toward an irreversible attached protein corona over time was observed and mass spectrometry of the digested protein coronia revealed albumin as the most abundant component which suggests an improved biocompatibility.
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IL-37: a new anti-inflammatory cytokine of the IL-1 family
Diana Boraschi,Davide Lucchesi,Stefan Hainzl,Maria Leitner,Elisabeth Maier,Doris Mangelberger,Gertie Janneke Oostingh,Tobias Pfaller,Claudia Pixner,Gernot Posselt,Paola Italiani,Marcel F. Nold,Claudia A. Nold-Petry,Philip Bufler,Charles A. Dinarello +14 more
TL;DR: The finding that IL-37 also locates to the nucleus, as do IL-1α and IL-33, for receptor-independent organ/tissue-specific regulation of inflammation is reviewed, which may explain some of the disparate biological effects that have been reported for mice deficient in the IL-18R.
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Hardening of the Nanoparticle–Protein Corona in Metal (Au, Ag) and Oxide (Fe3O4, CoO, and CeO2) Nanoparticles
TL;DR: Results show that production of reactive oxygen species is decreased if the nanoparticles are preincubated for 48 h with serum, and different temporal patterns of the protein corona formation are observed that can be considered a fingerprint for nanoparticle identification.
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Problems and challenges in the development and validation of human cell-based assays to determine nanoparticle-induced immunomodulatory effects
Gertie Janneke Oostingh,Eudald Casals,Paola Italiani,Renato Colognato,René Stritzinger,Jessica Ponti,Tobias Pfaller,Yvonne Kohl,Daniëlla Ooms,Flavia Favilli,H. Leppens,Davide Lucchesi,François Rossi,Inge Nelissen,Hagen Thielecke,Víctor F. Puntes,Albert Duschl,Diana Boraschi +17 more
TL;DR: The problems that were encountered in the immunological assay systems used in this study, such as chemical or endotoxin contamination and optical interference caused by the dense material, significantly affected the data obtained.
Journal ArticleDOI
The suitability of different cellular in vitro immunotoxicity and genotoxicity methods for the analysis of nanoparticle-induced events
Tobias Pfaller,Renato Colognato,Inge Nelissen,Flavia Favilli,Eudald Casals,Daniëlla Ooms,H. Leppens,Jessica Ponti,René Stritzinger,Víctor F. Puntes,Diana Boraschi,Albert Duschl,Gertie Janneke Oostingh +12 more
TL;DR: The results show that cytotoxicity as well as immunotoxicity and genotoxicity induced by these two inorganic nanoparticles was low or absent when using a panel of cell-based tests in different laboratories.