T
Tobias R. Kollmann
Researcher at Telethon Institute for Child Health Research
Publications - 198
Citations - 10070
Tobias R. Kollmann is an academic researcher from Telethon Institute for Child Health Research. The author has contributed to research in topics: Vaccination & Immune system. The author has an hindex of 48, co-authored 181 publications receiving 7929 citations. Previous affiliations of Tobias R. Kollmann include Yeshiva University & University of Washington.
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Journal ArticleDOI
Correlation analysis of intracellular and secreted cytokines via the generalized integrated mean fluorescence intensity
Parisa Shooshtari,Edgardo S. Fortuno,Darren Blimkie,Miao Yu,Arvind Gupta,Tobias R. Kollmann,Ryan R. Brinkman,Ryan R. Brinkman,Ryan R. Brinkman +8 more
TL;DR: This work investigated the correlation of the iMFI derived from a human innate immune response ICS assay with functional cytokine release into the culture supernatant, as innate cytokines need to be released to have a functional impact.
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Attenuated innate immune defenses in very premature neonates during the neonatal period
Elizabeth A. Marchant,Bernard Kan,Ashish Sharma,Alice van Zanten,Tobias R. Kollmann,Rollin Brant,Pascal M. Lavoie +6 more
TL;DR: Innate immune antimicrobial defenses are profoundly attenuated developmentally in very preterm neonates during the neonatal period, suggesting that exogenous factors drive the sustained systemic inflammation that has been linked to increased morbidities in these infants.
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Variation between Populations in the Innate Immune Response to Vaccine Adjuvants.
TL;DR: This review summarizes what is currently known about differences between populations around the world in the innate immune response to existing as well as new and promising vaccine adjuvants.
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Transfer of Maternal Antimicrobial Immunity to HIV-Exposed Uninfected Newborns.
TL;DR: Mother-targeting interventions to improve the health of infants born to HIV-infected women, such as immunization during pregnancy and reduction of maternal inflammation are summarized, which supports the recommendation to breast-feed during antiretroviral treatment to protect HIV-exposed infants.
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Linking susceptibility to infectious diseases to immune system abnormalities among HIV-exposed uninfected infants
TL;DR: The concept that specific types of infectious diseases that are more common among HEU infants could provide clues as to the potential underlying immunological abnormalities is explored.