T
Torben Plesner
Researcher at University of Southern Denmark
Publications - 205
Citations - 11134
Torben Plesner is an academic researcher from University of Southern Denmark. The author has contributed to research in topics: Daratumumab & Multiple myeloma. The author has an hindex of 45, co-authored 186 publications receiving 9295 citations. Previous affiliations of Torben Plesner include University of Copenhagen & Finsen Laboratory.
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Journal Article
Pharmacodynamic relationship between natural killer cells and daratumumab exposure in relapsed/refractory multiple myeloma
Tineke Casneuf,Xu Steven Xu,Iii Adams H.,Amy Axel,Bie Verbist,Kevin Liu,Imran Khan,Tahamtan Ahmadi,Xiaoyu Yan,Sagar Lonial,Torben Plesner,H. M. Lokhorst,N. van de Donk,Pamela L. Clemens,Amy Sasser +14 more
Journal ArticleDOI
Elotuzumab: serum protein electrophoresis and immunofixation interference with clinical assessment of M-protein response in relapsed/refractory multiple myeloma (RRMM)
M.A. Dimopoulos,Sagar Lonial,L.F. Casado,M. Golightly,Chantal Doyen,Suresh Shelat,J. Mora,Jessica Katz,Torben Plesner +8 more
TL;DR: POM+LoDEX was tolerable and demonstrated efficacy in RRMM pts regardless of age; across age groups, the safety profile and relative dose intensity were similar; PFS and response rates were also similar and consistent with previous findings.
Journal ArticleDOI
Daratumumab, lenalidomide, and dexamethasone (DRd) vs lenalidomide and dexamethasone (Rd) in relapsed or refractory multiple myeloma (RRMM): Efficacy and safety update (POLLUX).
Nizar J. Bahlis,Philippe Moreau,Hareth Nahi,Torben Plesner,Hartmut Goldschmidt,Kenshi Suzuki,Robert Z. Orlowski,Neil Rabin,Merav Leiba,Albert Oriol,Ajai Chari,Jesús F. San Miguel,Paul G. Richardson,Saad Z. Usmani,Lisa O'Rourke,Kaida Wu,Tineke Casneuf,Christopher Chiu,Xiang Qin,Meletios A. Dimopoulos +19 more
TL;DR: Daratumumab is a human CD38-targeting mAb that significantly prolongs progression-free survival (PFS) when added to standard-of-care regimens in patients with RRMM.
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Findings of Whole Body Computed Tomography Compared to Conventional Skeletal Survey in Patients with Monoclonal Plasma Cell Disorders - a Study of the International Myeloma Working Group
Jens Hillengass,Jens Hillengass,Lia A. Monopoulos,Stefan Delorme,Vassilis Koutoulidis,Thomas Hielscher,Jessica Engelhart,Matthew T. Drake,Vincent Rajkumar,Brian Østergaard,Niels Abildgaard,Maja Hinge,Torben Plesner,Yasuhito Suehara,Kosei Matsue,Jo Caers,Nadia Withofs,Meletios A. Dimopoulos,Hartmut Goldschmidt,Suzanne Lentzsch,Brian G.M. Durie,Evangelos Terpos +21 more
TL;DR: WBCT shows significantly more sites of bone destruction compared to conventional X-ray imaging particularly in skeletal regions composed primarily of trabecular bone while CSS shows more osteolyses in the appendicular skeleton.
Journal ArticleDOI
Enduring efficacy and tolerability of daratumumab in combination with lenalidomide and dexamethasone in patients with relapsed or relapsed/refractory multiple myeloma (GEN503): final results of an open-label, phase 1/2 study
Torben Plesner,Hendrik Tobias Arkenau,Monique C. Minnema,Mario Boccadoro,Philippe Moreau,Jamie Cavenagh,Aurore Perrot,Jacob P. Laubach,Jakub Krejcik,Tahamtan Ahmadi,Carla de Boer,Diana Chen,Christopher Chiu,Jordan M. Schecter,Paul G. Richardson +14 more
TL;DR: Clonal haemopoiesis and therapy-related myeloid malignancies in elderly patients: a proof-of-concept, case-control study.