J
Jo Caers
Researcher at University of Liège
Publications - 137
Citations - 7213
Jo Caers is an academic researcher from University of Liège. The author has contributed to research in topics: Multiple myeloma & Medicine. The author has an hindex of 27, co-authored 114 publications receiving 5221 citations. Previous affiliations of Jo Caers include Free University of Brussels & Cliniques Universitaires Saint-Luc.
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Journal ArticleDOI
International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma.
S. Vincent Rajkumar,Meletios A. Dimopoulos,Antonio Palumbo,Joan Bladé,Giampaolo Merlini,Maria-Victoria Mateos,Shaji Kumar,Jens Hillengass,Efstathios Kastritis,Paul G. Richardson,Ola Landgren,Bruno Paiva,Angela Dispenzieri,Brendan M. Weiss,Xavier Leleu,Sonja Zweegman,Sagar Lonial,Laura Rosiñol,Elena Zamagni,Sundar Jagannath,O. Sezer,Sigurdur Y. Kristinsson,Jo Caers,Saad Z. Usmani,Juan José Lahuerta,Hans Erik Johnsen,Meral Beksac,Michele Cavo,Hartmut Goldschmidt,Evangelos Terpos,Robert A. Kyle,Kenneth C. Anderson,Brian G.M. Durie,Jesús F. San Miguel +33 more
TL;DR: The disease definition of multiple myeloma is updated to include validated biomarkers in addition to existing requirements of attributable CRAB features (hypercalcaemia, renal failure, anaemia, and bone lesions), and specific metrics that new biomarkers should meet for inclusion in the disease definition are provided.
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Treatment of multiple myeloma with high-risk cytogenetics: a consensus of the International Myeloma Working Group
Pieter Sonneveld,Hervé Avet-Loiseau,Sagar Lonial,Saad Z. Usmani,David S. Siegel,Kenneth C. Anderson,Wee Joo Chng,Philippe Moreau,Michel Attal,Robert A. Kyle,Jo Caers,Jens Hillengass,Jesús F. San Miguel,Niels W.C.J. van de Donk,Hermann Einsele,Joan Bladé,Brian G.M. Durie,Hartmut Goldschmidt,Maria-Victoria Mateos,Antonio Palumbo,Robert Z. Orlowski +20 more
TL;DR: Based on data available today, bortezomib and carfilzomib treatment appear to improve complete response, progression-free survival, and overall survival in t(4;14) and del(17/17p), whereas lenalidomide may be associated with improved progression-based survival and progression- free survival int( 4;14), del( 17/17 p), and t(14;16), and gain(1q).
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Plasma cell leukemia: consensus statement on diagnostic requirements, response criteria and treatment recommendations by the International Myeloma Working Group
C. Fernández de Larrea,Robert A. Kyle,Brian G.M. Durie,Heinz Ludwig,Saad Z. Usmani,David H. Vesole,Roman Hájek,J F San Miguel,O. Sezer,Pieter Sonneveld,Shaji Kumar,Anuj Mahindra,Raymond L. Comenzo,Antonio Palumbo,A. Mazumber,KC Anderson,P. G. Richardson,Ashraf Badros,Jo Caers,Michele Cavo,Xavier Leleu,Meletios A. Dimopoulos,Chor S. Chim,Rik Schots,A. Noeul,Dorotea Fantl,Ulf-Henrik Mellqvist,Ola Landgren,Asher Chanan-Khan,Philippe Moreau,Rafael Fonseca,Giampaolo Merlini,J. J. Lahuerta,J. Bladé,Robert Z. Orlowski,Jatin J. Shah +35 more
TL;DR: It is proposed that the thresholds for diagnosis be re-examined and consensus recommendations are made for diagnosis, as well as, response and progression criteria.
Journal ArticleDOI
Galectin expression in cancer diagnosis and prognosis: a systematic review
TL;DR: In this paper, the authors present a systematic review of galectin expression in human cancer patients, showing that increased Galectin-1 expression is associated with poor prognosis while elevated Galectins-9 expression is emerging as a marker of favorable disease outcome.
Journal ArticleDOI
Management of relapsed multiple myeloma: recommendations of the International Myeloma Working Group
Jacob P. Laubach,Laurent Garderet,Anuj Mahindra,Gösta Gahrton,Jo Caers,O. Sezer,Peter M. Voorhees,Xavier Leleu,Hans Erik Johnsen,Matthew Streetly,Artur Jurczyszyn,Heinz Ludwig,U. H. Mellqvist,W. J. Chng,Linda M. Pilarski,H. Einsele,J. Hou,Ingemar Turesson,Elena Zamagni,C. S. Chim,Amitabha Mazumder,Jan Westin,Jiachuan Lu,Tony Reiman,Sigurdur Y. Kristinsson,Douglas E. Joshua,Murielle Roussel,Peter O'Gorman,E. Terpos,P.L. McCarthy,M.A. Dimopoulos,Philippe Moreau,Robert Z. Orlowski,J. S. Miguel,KC Anderson,Antonio Palumbo,Shaji Kumar,Vincent Rajkumar,Brian G.M. Durie,Paul G. Richardson +39 more
TL;DR: This comprehensive manuscript from the International Myeloma Working Group provides detailed recommendations on management of relapsed disease, with sections dedicated to diagnostic evaluation, determinants of therapy, and general approach to patients with specific disease characteristics.