T
Toshiaki Yujiri
Researcher at Yamaguchi University
Publications - 100
Citations - 3414
Toshiaki Yujiri is an academic researcher from Yamaguchi University. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 25, co-authored 97 publications receiving 3118 citations. Previous affiliations of Toshiaki Yujiri include National Jewish Health & Anschutz Medical Campus.
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Journal ArticleDOI
Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption.
TL;DR: Loss of MEKK1 expression resulted in a greater apoptotic response of cells to hyperosmolarity and microtubule disruption, and activated JNK normally in response to heat shock, anisomycin, and ultraviolet irradiation.
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Molecular mimicry by Helicobacter pylori CagA protein may be involved in the pathogenesis of H. pylori‐associated chronic idiopathic thrombocytopenic purpura
Toru Takahashi,Toshiaki Yujiri,Kenji Shinohara,Yusuke Inoue,Yutaka Sato,Fujii Y,Masashi Okubo,Yuzuru Zaitsu,Koichi Ariyoshi,Yukinori Nakamura,Ryouhei Nawata,Yoshitomo Oka,Mutsunori Shirai,Yukio Tanizawa +13 more
TL;DR: Cross‐reactivity between PAIgG and H. pylori CagA protein suggests that molecular mimicry by Cag a plays a key role in the pathogenesis of a subset of cITP patients.
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MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation
Toshiaki Yujiri,Margaret F. Ware,Margaret F. Ware,Christian Widmann,Christian Widmann,Ryan Oyer,David Russell,Edward D. Chan,Yuzuru Zaitsu,Penny Clarke,Kenneth L. Tyler,Yoshitomo Oka,Gary R. Fanger,Peter M. Henson,Gary L. Johnson +14 more
TL;DR: MEKK1 senses microtubule integrity, contributes to the regulation of fibroblast and epithelial cell migration, and is required for activation of JNK but not NF-kappaB in response to selected stress stimuli.
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Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults
Takahiko Yasuda,Takahiko Yasuda,Shinobu Tsuzuki,Masahito Kawazu,Fumihiko Hayakawa,Shinya Kojima,Toshihide Ueno,Naoto Imoto,Shinji Kohsaka,Akiko Kunita,Koichiro Doi,Toru Sakura,Toshiaki Yujiri,Eisei Kondo,Katsumichi Fujimaki,Yasunori Ueda,Yasutaka Aoyama,Shigeki Ohtake,Junko Takita,Eirin Sai,Masafumi Taniwaki,Mineo Kurokawa,Shinichi Morishita,Masashi Fukayama,Hitoshi Kiyoi,Yasushi Miyazaki,Tomoki Naoe,Hiroyuki Mano +27 more
TL;DR: The data show that DUX4 can become an oncogenic driver as a result of somatic chromosomal rearrangements and that AYA-ALL may be a clinical entity distinct from ALL at other ages, and that Dux4 fusions were preferentially detected in the AYA generation.
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Anti-apoptotic versus pro-apoptotic signal transduction: Checkpoints and stop signs along the road to death
Matthew B. Jarpe,Christian Widmann,Cindy Knall,Thomas K. Schlesinger,Spencer B. Gibson,Toshiaki Yujiri,Gary R. Fanger,Erwin W. Gelfand,Gary L. Johnson +8 more
TL;DR: The activation of caspases is a final commitment step for apoptosis and it is now evident that signal transduction pathways involving specific protein kinases modulate the apoptotic response.