T
Toshio Mori
Researcher at Nara Medical University
Publications - 138
Citations - 6242
Toshio Mori is an academic researcher from Nara Medical University. The author has contributed to research in topics: Pyrimidine dimer & DNA damage. The author has an hindex of 41, co-authored 133 publications receiving 5894 citations. Previous affiliations of Toshio Mori include Osaka Yuhigaoka Gakuen Junior College & Stony Brook University.
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Journal ArticleDOI
UV-Induced Ubiquitylation of XPC Protein Mediated by UV-DDB-Ubiquitin Ligase Complex
Kaoru Sugasawa,Yuki Okuda,Masafumi Saijo,Ryotaro Nishi,Noriyuki Matsuda,Gilbert Chu,Toshio Mori,Shigenori Iwai,Keiji Tanaka,Kiyoji Tanaka,Fumio Hanaoka +10 more
TL;DR: It is shown that XPC undergoes reversible ubiquitylation upon UV irradiation of cells and that this depends on the presence of functional UV-DDB activity, which strongly suggest that ubiquitylated plays a critical role in the transfer of the UV-induced lesion from UV- DDB to XPC.
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Simultaneous establishment of monoclonal antibodies specific for either cyclobutane pyrimidine dimer or (6-4)photoproduct from the same mouse immunized with ultraviolet-irradiated DNA.
TL;DR: The first report of the simultaneous establishment of monoclonal antibodies against the two different types of photolesions from the same mouse is reported, which indicated that the epitope of 64M antibodies was the (6‐4)photoproduct in DNA.
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Spatial and temporal cellular responses to single-strand breaks in human cells.
TL;DR: The results show the importance of poly(ADP-ribosyl)ation in sequential cellular responses to SSB by creating SSB in restricted areas in the nucleus by the immediate action of UVDE on UV-induced DNA lesions.
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Localization of ADAMTS13 to the stellate cells of human liver.
Masahito Uemura,Kouko Tatsumi,Masanori Matsumoto,Masao Fujimoto,Tomomi Matsuyama,Masatoshi Ishikawa,Takaaki Iwamoto,Toshio Mori,Akio Wanaka,Hiroshi Fukui,Yoshihiro Fujimura +10 more
TL;DR: Results suggest that HSCs may be major cells producing ADAMTS13 in human liver, with positive signals exclusively in perisinusoidal cells with irregularly elongated dendritic processes extending between hepatocytes.
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Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein.
Ryotaro Nishi,Yuki Okuda,Eriko Watanabe,Toshio Mori,Shigenori Iwai,Chikahide Masutani,Kaoru Sugasawa,Fumio Hanaoka +7 more
TL;DR: Centrin 2 enhanced the cell-free NER dual incision and damaged DNA binding activities of XPC, which likely require physical interaction between XPC and centrin 2.