T
Toshiyuki Yamamoto
Researcher at Fukushima Medical University
Publications - 681
Citations - 8596
Toshiyuki Yamamoto is an academic researcher from Fukushima Medical University. The author has contributed to research in topics: Medicine & Psoriasis. The author has an hindex of 42, co-authored 598 publications receiving 7643 citations. Previous affiliations of Toshiyuki Yamamoto include University of Cologne & Tokyo Medical and Dental University.
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CONFLICT OF INTEREST: None declared.
TL;DR: A rare case of hidradenitis suppurativa (HS), diagnosed by definition criteria, with multiple subcutaneous abscesses with spontaneous drainage of pus, sub cutaneousindurations and scars in bilateral inguinal areas, which had appeared 10 years prior and rapidly increased in number.
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Clinically mild encephalitis/encephalopathy with a reversible splenial lesion
Hiroko Tada,Jun-ichi Takanashi,A. J. Barkovich,H. Oba,Masayuki Maeda,Hirokazu Tsukahara,Motomasa Suzuki,Toshiyuki Yamamoto,Taro Shimono,Takashi Ichiyama,Toshiaki Taoka,O. Sohma,H. Yoshikawa,Yoichi Kohno +13 more
TL;DR: In this article, the splenium of the corpus callosum (SCC) was ovoid in six patients; it extended irregularly from the center to the lateral portion of SCC in the other eight patients; homogeneously reduced diffusion was seen in all seven patients who underwent diffusion-weighted imaging.
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Animal model of sclerotic skin. I: Local injections of bleomycin induce sclerotic skin mimicking scleroderma
Toshiyuki Yamamoto,Shinsuke Takagawa,Ichiro Katayama,Kenshi Yamazaki,Yoichiro Hamazaki,Hiroshi Shinkai,Kiyoshi Nishioka +6 more
TL;DR: The results suggest that dermal sclerosis induced by BLM closely resembles systemic sclerosis both histologically and biochemically.
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Monocyte chemoattractant protein-1 enhances gene expression and synthesis of matrix metalloproteinase-1 in human fibroblasts by an autocrine IL-1 alpha loop.
TL;DR: It is shown that recombinant human MCP-1 affects gene expression of interstitial collagenase (matrix metalloproteinase-1 (MMP-1) in primary human skin fibroblasts and a stable fibroblast cell line and provides evidence that this is mediated by an IL-1α autocrine loop.
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Effect of Interleukin-10 on the Gene Expression of Type I Collagen, Fibronectin, and Decorin in Human Skin Fibroblasts: Differential Regulation by Transforming Growth Factor-β and Monocyte Chemoattractant Protein-1
TL;DR: Investigation of the effect of IL-10 on gene expression of extracellular matrix (ECM) proteins, such as type I collagen, fibronectin, and decorin, in human skin fibroblasts shows that it differentially regulates TGF-beta and MCP-1 in the modulation of ECM proteins and suggests that IL- 10 plays a role in the regulation of tissue remodeling.