T
Tribhuwan Yadav
Researcher at Harvard University
Publications - 15
Citations - 1142
Tribhuwan Yadav is an academic researcher from Harvard University. The author has contributed to research in topics: DNA repair & DNA. The author has an hindex of 14, co-authored 15 publications receiving 798 citations. Previous affiliations of Tribhuwan Yadav include Yale University & Spanish National Research Council.
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Journal ArticleDOI
Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1
TL;DR: In addition to sensing DNA damage and replication stress, RPA is a sensor of R loops and a regulator of RNaseH1, extending the versatile role of RPA in suppression of genomic instability.
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Alternative Lengthening of Telomeres through Two Distinct Break-Induced Replication Pathways.
TL;DR: An assay is described to visualize ALT-mediated telomeric DNA synthesis in AlT-associated PML bodies (APBs) without DNA-damaging agents or replication inhibitors, suggesting that ALT occurs through a RAD52-dependent and a RAD 52-independent BIR pathway.
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Double-strand break repair in bacteria: a view from Bacillus subtilis.
Silvia Ayora,Begoña Carrasco,Paula P. Cárdenas,Carolina Elvira César,Cristina Cañas,Tribhuwan Yadav,Chiara Marchisone,Juan C. Alonso +7 more
TL;DR: The functions that are known to contribute to DNA DSB repair in B. subtilis are examined, and their properties are compared with those of other bacterial phyla.
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ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB
Yaqun Teng,Tribhuwan Yadav,Meihan Duan,Meihan Duan,Jun Tan,Yufei Xiang,Boya Gao,Jianquan Xu,Zhuobin Liang,Yang Liu,Satoshi Nakajima,Yi Shi,Arthur S. Levine,Lee Zou,Li Lan +14 more
TL;DR: It is demonstrated that R loops are induced by ROS at the transcribed genome, triggering a CSB-RAD52- dependent but BRCA1/2-independent RAD51 loading for repair.
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Genetic recombination in Bacillus subtilis : a division of labor between two single-strand DNA-binding proteins
Tribhuwan Yadav,Begoña Carrasco,Angela R. Myers,Nicholas P. George,James L. Keck,Juan C. Alonso +5 more
TL;DR: The results provide a mechanistic framework for rationalizing the coordinated events modulated by SsbA, SsbB and RecO that are crucial for RecA-dependent chromosomal transformation andRecA-independent plasmid transformation.