T
Trivikram R. Molugu
Researcher at University of Arizona
Publications - 23
Citations - 508
Trivikram R. Molugu is an academic researcher from University of Arizona. The author has contributed to research in topics: Nuclear magnetic resonance spectroscopy & Membrane. The author has an hindex of 7, co-authored 20 publications receiving 302 citations. Previous affiliations of Trivikram R. Molugu include University of Hyderabad & Council of Scientific and Industrial Research.
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Journal ArticleDOI
How cholesterol stiffens unsaturated lipid membranes
Saptarshi Chakraborty,Milka Doktorova,Trivikram R. Molugu,Frederick A. Heberle,Haden L. Scott,Boris Dzikovski,Michihiro Nagao,Laura Stingaciu,Robert F. Standaert,Francisco N. Barrera,John Katsaras,George Khelashvili,Michael F. Brown,Rana Ashkar +13 more
TL;DR: The current findings point to a scale-dependent manifestation of membrane properties, highlighting the need to reassess cholesterol’s role in controlling membrane bending rigidity over mesoscopic length and time scales of important biological functions, such as viral budding and lipid–protein interactions.
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Area per Lipid and Cholesterol Interactions in Membranes from Separated Local-Field 13C NMR Spectroscopy
TL;DR: These studies show that solid-state (13)C NMR spectroscopy is applicable to investigations of complex lipids and makes it possible to obtain structural parameters for biomembrane systems where isotope labeling may be prohibitive.
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Concepts and Methods of Solid-State NMR Spectroscopy Applied to Biomembranes.
TL;DR: This review demonstrates the principles and applications ofSolid-state NMR by unifying dipolar and quadrupolar interactions and highlights the unique features offered by solid-state 2H NMR with experimental illustrations.
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In vitro evolved non-aggregating and thermostable lipase: structural and thermodynamic investigation.
Md. Zahid Kamal,Shoeb Ahmad,Trivikram R. Molugu,Amash Vijayalakshmi,Mandar V. Deshmukh,Rajan Sankaranarayanan,Nalam Madhusudhana Rao +6 more
TL;DR: The study suggest that better anchoring of the loops with the rest of the protein molecule through mutations particularly on the sites that perturb/disturb the exposed hydrophobic patches can simultaneously increase protein stability and aggregation resistance.
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Cholesterol-induced suppression of membrane elastic fluctuations at the atomistic level
TL;DR: Applications of solid-state NMR spectroscopy for investigating the influences of lipid-cholesterol interactions on membrane fluctuations are reviewed and opposite influences of cholesterol and detergents on collective dynamics and elasticity at an atomistic scale are inferred.