T
Tsung-Ping Su
Researcher at National Institute on Drug Abuse
Publications - 148
Citations - 13210
Tsung-Ping Su is an academic researcher from National Institute on Drug Abuse. The author has contributed to research in topics: Receptor & Sigma-1 receptor. The author has an hindex of 59, co-authored 143 publications receiving 12102 citations. Previous affiliations of Tsung-Ping Su include United States Department of Health and Human Services & University of Kentucky.
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Journal ArticleDOI
Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival
Teruo Hayashi,Tsung-Ping Su +1 more
TL;DR: The results reveal that the orchestrated ER chaperone machinery at MAM, by sensing ER Ca(2+) concentrations, regulates ER-mitochondrial interorganellar Ca( 2+) signaling and cell survival.
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MAM: more than just a housekeeper
TL;DR: The MAM thus integrates signal transduction with metabolic pathways to regulate the communication and functional interactions between the ER and mitochondrion and enables highly efficient transmission of Ca(2+) from the ER to mitochondria to stimulate oxidative metabolism and, conversely, might enable the metabolically energized mitochondria
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The Pharmacology of Sigma-1 Receptors
Tangui Maurice,Tsung-Ping Su +1 more
TL;DR: It is found that the most prominent action of sigma-1 receptors in biological systems including cell lines, primary cultures, and animals is the regulation and modulation of voltage-regulated and ligand-gated ion channels, including Ca(2-)-, K(+)-, Na(+), Cl(-), and SK channels, and NMDA and IP3 receptors.
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Time-Dependent Increases in Brain-Derived Neurotrophic Factor Protein Levels within the Mesolimbic Dopamine System after Withdrawal from Cocaine: Implications for Incubation of Cocaine Craving
TL;DR: Time-dependent increases in BDNF levels may lead to synaptic modifications that underlie enhanced responsiveness to cocaine cues after prolonged withdrawal periods, and these changes were observed during tests for sucrose craving.
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Steroid Binding at σ Receptors Suggests a Link between Endocrine, Nervous, and Immune Systems
TL;DR: The findings suggest that steroids are naturally occurring ligands for sigma receptors and raise the possibility that these sites mediate some aspects of steroid-induced mental disturbances and alterations in immune functions.