U
Ulrike Scheib
Researcher at Humboldt University of Berlin
Publications - 14
Citations - 356
Ulrike Scheib is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Rhodopsin & Cyclase. The author has an hindex of 8, co-authored 13 publications receiving 280 citations. Previous affiliations of Ulrike Scheib include Max Planck Society & University of California, San Diego.
Papers
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Journal ArticleDOI
The rhodopsin–guanylyl cyclase of the aquatic fungus Blastocladiella emersonii enables fast optical control of cGMP signaling
Ulrike Scheib,Katja Stehfest,Christine E. Gee,Heinz G. Körschen,Roman Fudim,Thomas G. Oertner,Peter Hegemann +6 more
TL;DR: RhGC is proposed as a versatile tool for the optogenetic analysis of cGMP-dependent signaling processes in cell biology and the neurosciences.
Journal ArticleDOI
Structure and Glycolipid Binding Properties of the Nematicidal Protein Cry5B
TL;DR: The protoxin form of Cry5B was found to bind nematode glycolipids with a specificity equal to that of activatedcry5B, but with lower affinity, which suggests that the initial binding ofCry5B protoxin to gly colipids can be stabilized at the nematodes cell surface by proteolysis.
Journal ArticleDOI
Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain
Ulrike Scheib,Matthias Broser,Oana M Constantin,Shang Yang,Shiqiang Gao,Shatanik Mukherjee,Katja Stehfest,Georg Nagel,Christine E. Gee,Peter Hegemann +9 more
TL;DR: The characterization of the rhodopsin-guanylyl cyclase from Catenaria anguillulae (CaRhGC), which produces cGMP in response to green light with a light to dark activity ratio >1000, demonstrates the usability of these cyclases for optogenetic applications.
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Bacillus thuringiensis-derived Cry5B Has Potent Anthelmintic Activity against Ascaris suum
TL;DR: It is demonstrated for the first time that A. suum expresses the receptors for Bacillus thuringiensis crystal protein and novel anthelmintic Cry5B, which has been previously shown to intoxicate hookworms and which belongs to a class of proteins considered non-toxic to vertebrates.
Journal ArticleDOI
Upgrading a microplate reader for photobiology and all-optical experiments
Florian Richter,Ulrike Scheib,Jennifer Mehlhorn,Roman Schubert,Jonas Wietek,Oliver Gernetzki,Peter Hegemann,Tilo Mathes,Tilo Mathes,Andreas Möglich +9 more
TL;DR: In this article, the authors use inexpensive open-source electronics to add programmable illumination capabilities to a multimode microplate reader, which is used to characterize light-triggered phenomena in three different sensory photoreceptors.