U
Umesh C. S. Yadav
Researcher at Jawaharlal Nehru University
Publications - 86
Citations - 3314
Umesh C. S. Yadav is an academic researcher from Jawaharlal Nehru University. The author has contributed to research in topics: Inflammation & Aldose reductase. The author has an hindex of 26, co-authored 82 publications receiving 2536 citations. Previous affiliations of Umesh C. S. Yadav include University of Texas System & Central University of Gujarat.
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Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies.
TL;DR: The aspects of metabolic disorders-induced oxidative stress in major pathological conditions and strategies for their prevention and therapy are discussed.
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Cell-death assessment by fluorescent and nonfluorescent cytosolic and nuclear staining techniques.
TL;DR: These techniques help in differentiating several cellular and nuclear phenotypes that result from DNA damage and have been identified as specific to necrosis or early and late apoptosis as well as scores of other nuclear deformities occurring inside the cells.
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Pharmacological effects of Trigonella foenum-graecum L. in health and disease
TL;DR: The resarch on Trigonella exhibits its health benefits and potential medicinal properties in various indications and has little or no side effects, suggesting its pharmaceutical, therapeutic and nutritional potential.
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Regulation of NF-κB-induced inflammatory signaling by lipid peroxidation-derived aldehydes.
Umesh C. S. Yadav,Kota V. Ramana +1 more
TL;DR: The mechanisms by which the lipid aldehydes transduce activation of NF-κB signaling pathways that may help to develop therapeutic strategies for the prevention of a number of inflammatory diseases are described.
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Aldose reductase inhibition suppresses oxidative stress-induced inflammatory disorders.
Satish K. Srivastava,Umesh C. S. Yadav,Aramati B.M. Reddy,Ashish Saxena,Ravinder Tammali,Mohammad Shoeb,Naseem H. Ansari,Aruni Bhatnagar,Mark Petrash,Sanjay K. Srivastava,Kota V. Ramana +10 more
TL;DR: Fidarestat is demonstrated that AKR1B1 inhibitor, fidarestat, significantly prevents tumor necrosis factor-alpha (TNF-α)-, growth factors-, lipopolysachharide (LPS)-, and environmental allergens-induced inflammatory signals that cause various inflammatory diseases.