U
Ursula B. Kaiser
Researcher at Brigham and Women's Hospital
Publications - 232
Citations - 16273
Ursula B. Kaiser is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Gonadotropin-releasing hormone & Receptor. The author has an hindex of 62, co-authored 210 publications receiving 14115 citations. Previous affiliations of Ursula B. Kaiser include University of Pennsylvania & St. Michael's Hospital.
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Journal ArticleDOI
GnRH-A Key Regulator of FSH.
George A. Stamatiades,George A. Stamatiades,George A. Stamatiades,Rona S. Carroll,Ursula B. Kaiser +4 more
TL;DR: The overarching goal of this review is to expand the understanding of the mechanisms and pathways underlying the carefully orchestrated control of FSH synthesis and secretion by GnRH, focusing on the transcriptional regulation of the Fshb gene.
Journal ArticleDOI
The gonadotropin-releasing hormone (GnRH) neuronal population is normal in size and distribution in GnRH-deficient and GnRH receptor-mutant hypogonadal mice.
John C. Gill,Brandon Wadas,Peilin Chen,Wendy Portillo,Andrea Reyna,Elisa M. Jorgensen,Shaila K. Mani,Gerald A. Schwarting,Suzanne M. Moenter,Stuart A. Tobet,Ursula B. Kaiser +10 more
TL;DR: Analysis of mouse strains and results establish that autocrine-paracrine GnRH-signaling is not a prerequisite for the developmental migration of GnRH neurons into the brain or for the projection of Gn RH neurosecretory axons.
Journal ArticleDOI
Tac1 Signaling Is Required for Sexual Maturation and Responsiveness of GnRH Neurons to Kisspeptin in the Male Mouse.
Caroline A Maguire,Yong Bhum Song,Min Wu,Silvia Leon,Rona S. Carroll,Meenakshi Alreja,Ursula B. Kaiser,Víctor M. Navarro +7 more
TL;DR: In this paper, the tachykinins substance P (SP) and neurokinin A (Tac1) have emerged as novel regulators of kisspeptin/GnRH release.
Journal ArticleDOI
Chromosomal Localization of the Gonadotropin-Releasing Hormone Receptor Gene to Human Chromosome 4q13.1-q21.1 and Mouse Chromosome 5
TL;DR: The murine GRHR gene was localized to mouse chromosome 5, linked to the endogenous retroviral marker Pmv-11, consistent with evolutionary conservation of homology between these two regions, as has been previously suggested from comparative mapping of several other loci.
Journal ArticleDOI
RF9 Acts as a KISS1R Agonist In Vivo and In Vitro
Le Min,Silvia Leon,Huan Li,Leonor Pinilla,Rona S. Carroll,Manuel Tena-Sempere,Manuel Tena-Sempere,Ursula B. Kaiser +7 more
TL;DR: This study demonstrates that RF9 acts primarily as a KISS1R agonist, but not as an allosteric modulator, to stimulate LH secretion, which raises questions regarding the utility of RF9 for assessing NPFF1R function and de-emphasize a predominant role of this signaling system in central regulation of reproduction.