Ursula Feiler

TL;DR: It is concluded that functional NST requires adequate substrate supply and cardiac function, but does not depend on ATGL-mediated lipolysis in BAT, suggesting that circulating energy substrates are sufficient to fuel NST.

TL;DR: These findings reveal an essential role for STAT5 in maintaining lipid homeostasis in white adipose tissue and provide a rationale for future studies into the potential of STAT5 manipulation to improve outcomes in metabolic diseases.

TL;DR: Fabps modulate Atgl-mediated TG hydrolysis and link lipolysis with intracellular lipid ligand shuttling and enhance the ability of Atgl/Cgi-58-mediatedlipolysis to induce the activity of peroxisome proliferator-activated receptors.

TL;DR: A critical role is suggested for Ces2c in intestinal lipid metabolism and the importance of intestinal lipolysis to protect mice from the development of hepatic insulin resistance, NAFLD, and excessive diet‐induced weight gain during metabolic stress.

TL;DR: In this paper , the authors present a multiorgan disorder, cancer-associated cachexia (CAC), which is a wasting syndrome drastically reducing efficacy of chemotherapy and life expectancy of patients.