V
Vasileios Atsaves
Researcher at Ludwig Institute for Cancer Research
Publications - 6
Citations - 227
Vasileios Atsaves is an academic researcher from Ludwig Institute for Cancer Research. The author has contributed to research in topics: Chimeric antigen receptor & Phenotype. The author has an hindex of 3, co-authored 4 publications receiving 145 citations. Previous affiliations of Vasileios Atsaves include University of Texas MD Anderson Cancer Center & National and Kapodistrian University of Athens.
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Journal ArticleDOI
AP-1 Transcription Factors as Regulators of Immune Responses in Cancer
TL;DR: This review will attempt to unravel the roles of AP-1 in theregulation of anti-tumor immune responses, with a focus on the regulation of immune checkpoints and Tregs, seeking to extract useful insights for more efficacious immunotherapy.
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Suppression of Jab1/CSN5 induces radio- and chemo-sensitivity in nasopharyngeal carcinoma through changes to the DNA damage and repair pathways
TL;DR: Jab1 is a novel biomarker for predicting the outcome of patients with NPC who are treated with DNA-damaging agents because of its important role in the cellular response to cisplatin and irradiation by regulating DNA damage and repair pathways.
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Expression of serine 194–phosphorylated Fas-associated death domain protein correlates with proliferation in B-cell non–Hodgkin lymphomas
Elias Drakos,Vasiliki Leventaki,Vasileios Atsaves,Vasileios Atsaves,Ellen J. Schlette,Pei Lin,Francisco Vega,Roberto N. Miranda,Francois Xavier Claret,L. Jeffrey Medeiros,George Z. Rassidakis,George Z. Rassidakis +11 more
TL;DR: In reactive lymph nodes, serine 194 phosphorylated Fas-associated death domain protein is expressed predominantly in the dark (proliferative) zone of germinal centers and has features of a novel proliferation marker.
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Soluble trivalent engagers redirect cytolytic T cell activity toward tumor endothelial marker 1.
Julie K. Fierle,Matteo Brioschi,Mariastella de Tiani,Laureline Wetterwald,Vasileios Atsaves,Johan Abram-Saliba,Tatiana V. Petrova,George Coukos,George Coukos,Steven M. Dunn +9 more
TL;DR: In this article, the authors presented two fully human anti-TEM1 single-chain variable fragment (scFv) reagents, namely, 1C1m and 7G22, that recognize distinct regions of the extracellular domain and possess substantially different affinities.
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A cell-based phenotypic library selection and screening approach for the de novo discovery of novel functional chimeric antigen receptors
Julie K. Fierle,Johan Abram-Saliba,Vasileios Atsaves,Matteo Brioschi,Mariastella de Tiani,Patrick Reichenbach,Melita Irving,George Coukos,Steven M. Dunn +8 more
TL;DR: This article explored the potential of an in vitro phenotypic CAR library discovery approach that tightly associates antibody-driven bridging of tumor and effector T cells with an informative and functionally relevant CAR activation signal.