V
Veronica Papa
Researcher at University of Naples Federico II
Publications - 37
Citations - 1412
Veronica Papa is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Protein kinase B & Medicine. The author has an hindex of 15, co-authored 30 publications receiving 1241 citations. Previous affiliations of Veronica Papa include University of Cassino & University of Bologna.
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Journal ArticleDOI
MMP Activity in the Hybrid Layer Detected with in situ Zymography
Annalisa Mazzoni,Fabio D. Nascimento,M. R. O. Carrilho,Ivarne L.S. Tersariol,Veronica Papa,Leo Tjäderhane,R. Di Lenarda,Fr Tay,David H. Pashley,Lorenzo Breschi +9 more
TL;DR: Investigating the HL gelatinolytic activity by in situ zymography and functional enzyme activity assay demonstrates, for the first time, intrinsic MMP activity in the HL, and intense activation of matrix-bound M MP activity with both etching and adhesive application.
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Multidrug resistance-associated protein 1 expression is under the control of the phosphoinositide 3 kinase/Akt signal transduction network in human acute myelogenous leukemia blasts
P. L. Tazzari,Alessandra Cappellini,Francesca Ricci,Camilla Evangelisti,Veronica Papa,Tiziana Grafone,Giovanni Martinelli,Roberto Conte,Lucio Cocco,James A. McCubrey,Alberto M. Martelli,Alberto M. Martelli +11 more
TL;DR: Evidence is presented that MRP1, but not P-gp, expression is under the control of the PI3K/Akt axis in AML blasts, and data suggest that PI3k/AKT activation may lead to the development of chemoresistance inAML blasts through a mechanism involving a p53-dependent suppression of MRP 1 expression.
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Teaching anatomy in the XXI century: New aspects and pitfalls
Veronica Papa,Mauro Vaccarezza +1 more
TL;DR: Traditional anatomy education based on topographical structural anatomy taught in lectures and gross dissection classes has been replaced by a multiple range of study modules, including problem-based learning, plastic models or computer-assisted learning, and curricula integration.
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Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells
Veronica Papa,P. L. Tazzari,Francesca Chiarini,Alessandra Cappellini,Francesca Ricci,Anna Maria Billi,Camilla Evangelisti,Emanuela Ottaviani,Giovanni Martinelli,Nicoletta Testoni,James A. McCubrey,Alberto M. Martelli +11 more
TL;DR: The findings indicate that perifosine, either alone or in combination with existing drugs, might be a promising therapeutic agent for the treatment of those AML cases characterized by upregulation of the PI3K–Akt survival pathway.
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Synergistic Proapoptotic Activity of Recombinant TRAIL Plus the Akt Inhibitor Perifosine in Acute Myelogenous Leukemia Cells
Pier Luigi Tazzari,Giovanna Tabellini,Francesca Ricci,Veronica Papa,Roberta Bortul,Francesca Chiarini,Camilla Evangelisti,Giovanni Martinelli,Andrea Bontadini,Lucio Cocco,James A. McCubrey,Alberto M. Martelli +11 more
TL;DR: The combination of perifosine and TRAIL might offer a novel therapeutic strategy for AML, and the combined treatment negatively affected the clonogenic activity of CD34(+) cells from patients with AML.