Pier Luigi Tazzari

TL;DR: AM-hMSCs may emerge as a remarkable tool for the cell therapy of multiple diseased tissues due to their angiogenic potential and may also pave the way for novel approaches in the development of tissue-engineered vascular grafts which are useful when vascularization of ischemic tissues is required.

TL;DR: The increased binding of TEC-11 to tumor vasculature and to dividing as opposed to noncycling HUVECs in vitro suggests that endoglin is an endothelial cell proliferation-associated marker, which might have therapeutic value in the treatment of solid tumors in humans.

TL;DR: The novel finding that CTLA‐4 molecule is expressed and functional on human tumor cells opens up the possibility of antitumor therapeutic intervention based on targeting this molecule.

TL;DR: Results indicate that longitudinal inhibition at two nodes of the PI3K/Akt/mTOR network with NVP-BEZ235, either alone or in combination with chemotherapeutic drugs, may be an efficient treatment of those T-ALLs that have aberrant upregulation of this signaling pathway for their proliferation and survival.

TL;DR: The most recent findings that may explain why the nucleus displays these striking modifications of apoptosis are reviewed, and the emerging evidence about apoptotic events as a trigger for the generation of autoantibodies to nuclear components is taken into consideration.