V
Vicky E MacRae
Researcher at University of Edinburgh
Publications - 91
Citations - 3164
Vicky E MacRae is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Calcification & Vascular smooth muscle. The author has an hindex of 30, co-authored 83 publications receiving 2566 citations. Previous affiliations of Vicky E MacRae include Royal Hospital for Sick Children & The Roslin Institute.
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The appearance and modulation of osteocyte marker expression during calcification of vascular smooth muscle cells.
TL;DR: A fuller understanding of the functional role of osteocyte formation and specifically sclerostin and E11 expression in the vascular calcification process may identify novel potential therapeutic strategies for clinical intervention.
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The importance of the SIBLING family of proteins on skeletal mineralisation and bone remodelling
TL;DR: The nature and extent of their proteolytic processing and post-translational modification affect their functional role and the likely roles of the SIBLING proteins in clinical disorders of hypophosphataemia and their potential therapeutic use are described.
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Altered Bone Development and an Increase in FGF-23 Expression in Enpp1−/− Mice
Neil Mackenzie,Dongxing Zhu,Elspeth Milne,Rob van't Hof,Aline Martin,Darryl L. Quarles,José Luis Millán,Colin Farquharson,Vicky E MacRae +8 more
TL;DR: It is concluded that NPP1 is essential for normal bone development and control of physiological bone mineralization in juvenile and adult mice.
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Characterisation of matrix vesicles in skeletal and soft tissue mineralisation
TL;DR: The characteristics MVs possess that enable them to participate in mineral deposition are reviewed, the content of skeletal tissue- and soft tissue-derived MVs are outlined, and their key mineralisation mediators that could be targeted for future therapeutic use are discussed.
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Skeletal muscle fibre growth and growth associated myopathy in the domestic chicken (Gallus domesticus).
TL;DR: Oestrogen may stimulate muscle fibre regeneration and recovery as a myo-protective adaptation to potentially detrimental changes in calcium economy during egg production.