Victor J. Feron

TL;DR: In this paper, the authors compared the estimated oral intake with a threshold of toxicological concern derived from chronic oral toxicity data for structurally-related compounds, and showed that the oral TTC values are valid for topical exposures and that relationship between the external topical dose and the internal dose can be taken into account by conservative default adjustment factors.

TL;DR: Overall assessment of the cancer risk of aldehydes in the diet leads to the conclusion that formaldehyde, acrolein, citral and vanillin are no dietary risk factors, and that the opposite may be true for acetaldehyde, crotonaldehyde and furfural.

TL;DR: In this paper, the authors hypothesize that, as a rule, exposure to mixtures of chemicals at (low) non-toxic doses of the individual constituents is of no health concern.

TL;DR: Present exposure to methyl eugenol and estragole resulting from consumption of food, mainly spices and added as such, does not pose a significant cancer risk.

TL;DR: It was concluded that under the conditions of the present study acetaldehyde is both cytotoxic and carcinogenic to the nasal mucosa of rats.