V
Victor May
Researcher at University of Vermont
Publications - 110
Citations - 4917
Victor May is an academic researcher from University of Vermont. The author has contributed to research in topics: Receptor & Pituitary adenylate cyclase-activating peptide. The author has an hindex of 36, co-authored 107 publications receiving 4323 citations.
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Journal ArticleDOI
Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor
Kerry J. Ressler,Kerry J. Ressler,Kerry J. Ressler,Kristina B. Mercer,Bekh Bradley,Bekh Bradley,Tanja Jovanovic,Amy Mahan,Kimberly Kerley,Seth D. Norrholm,Seth D. Norrholm,Varun Kilaru,Alicia K. Smith,Amanda J. Myers,Manuel Ramirez,Anzhelika Engel,Sayamwong E. Hammack,Donna J. Toufexis,Donna J. Toufexis,Karen M. Braas,Elisabeth B. Binder,Victor May +21 more
TL;DR: Data suggest that perturbations in the PACAP–PAC1 pathway are involved in abnormal stress responses underlying PTSD, and sex-specific effects may occur via oestrogen regulation of ADCYAP1R1.
Journal ArticleDOI
Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide: IUPHAR review 1.
Anthony J. Harmar,Jan Fahrenkrug,Illana Gozes,Marc Laburthe,Victor May,Joseph R. Pisegna,David Vaudry,Hubert Vaudry,James A. Waschek,Sami I. Said +9 more
TL;DR: The existing nomenclature for these receptors is confirmed, the current understanding of their structure, pharmacology and functions and their likely physiological roles in health and disease are reviewed.
Journal ArticleDOI
Chronic stress increases pituitary adenylate cyclase-activating peptide (PACAP) and brain-derived neurotrophic factor (BDNF) mRNA expression in the bed nucleus of the stria terminalis (BNST): roles for PACAP in anxiety-like behavior
Sayamwong E. Hammack,Joseph Y. Cheung,Kimberly M. Rhodes,Kristin C. Schutz,William A. Falls,Karen M. Braas,Victor May +6 more
TL;DR: Following chronic stress, quantitative transcript assessments of brain regions demonstrated dramatic increases in PACAP and PAC(1) receptor, BDNF, and TrkB receptor mRNA expression selectively in the dorsal aspect of the anterolateral bed nucleus of the stria terminalis (dBNST).
Journal ArticleDOI
Roles for Pituitary Adenylate Cyclase-Activating Peptide (PACAP) Expression and Signaling in the Bed Nucleus of the Stria Terminalis (BNST) in Mediating the Behavioral Consequences of Chronic Stress
Sayamwong E. Hammack,Carolyn W. Roman,Kimberly R. Lezak,Margaret Kocho-Shellenberg,Bethany Grimmig,William A. Falls,Karen M. Braas,Victor May +7 more
TL;DR: Evidence is reviewed that suggests that pituitary adenylate cyclase-activating polypeptide (PACAP) and corticotropin-releasing hormone (CRH) work together to modulate BNST function and increase anxiety-like behavior and how interactions between PACAP and CRH in the BN ST may mediate stress-associated behaviors.
Journal ArticleDOI
Pituitary adenylate cyclase-activating polypeptides directly stimulate sympathetic neuron neuropeptide Y release through PAC(1) receptor isoform activation of specific intracellular signaling pathways.
Karen M. Braas,Victor May +1 more
TL;DR: Pituitary adenylate cyclase-activating polypeptides have potent regulatory and neurotrophic activities on superior cervical ganglion (SCG) sympathetic neurons with pharmacological profiles consistent for the PACAP-selective PAC1 receptor, and preferential sympathetic neuron expression of PACAP