Victor Mudhune

TL;DR: ARS drugs were detected in follow-up samples from participants who were not receiving study-administered treatment and may be useful in addition to self-report of ARV drug use in some clinical trial settings.

TL;DR: The intervention arm showed significant gains in sexual health-related knowledge and self-efficacy and behavioral intention for risk-avoidance strategies and sexual risk communication compared with the control arm at T3, which supports the need for further research to assess the efficacy of the game-based intervention.

TL;DR: This study shows the strong acceptability of an interactive smartphone-based game both to adolescents and their parents in western Kenya and that of the study methods used to pilot-test the intervention, and suggests that longitudinal efficacy studies of this type of intervention, including those using biomarkers, have the potential to be acceptable among parents.

TL;DR: Two-way MPI did not significantly improve week 48 suppression, but it did modestly affect virological failure, and people failing second-line ART might not achieve benefits from phone-based triggers or enhanced adherence support (or both).

TL;DR: Although CD4 cell count increased substantially over time, there was no significant association with adherence by the methods, and persons with ≥95% adherence by any method used in this study were more likely to have a favorable treatment outcome.