V
Vinod Labhasetwar
Researcher at Cleveland Clinic Lerner Research Institute
Publications - 162
Citations - 23374
Vinod Labhasetwar is an academic researcher from Cleveland Clinic Lerner Research Institute. The author has contributed to research in topics: Drug delivery & Drug carrier. The author has an hindex of 61, co-authored 158 publications receiving 21673 citations. Previous affiliations of Vinod Labhasetwar include University of Michigan & University of Nebraska Medical Center.
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Journal ArticleDOI
Immune response with biodegradable nanospheres and alum: studies in rabbits using staphylococcal enterotoxin B-toxoid.
TL;DR: It is suggested that biodegradable nanospheres could be used as a vaccine adjuvant after sustained release of the toxoid under in vitro conditions.
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Antioxidant Therapy in Oxidative Stress-Induced Neurodegenerative Diseases: Role of Nanoparticle-Based Drug Delivery Systems in Clinical Translation
Anushruti Ashok,Syed Suhail Andrabi,Saffar Mansoor,Youzhi Kuang,Brian K. Kwon,Vinod Labhasetwar +5 more
TL;DR: A comprehensive analysis of the potential of antioxidant therapy, challenges in their clinical translation, and the role nanoparticles/drug delivery systems could play in addressing these challenges is provided.
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Nanoparticle-mediated p53 gene therapy for tumor inhibition
Blanka Sharma,Wenxue Ma,Wenxue Ma,Isaac M. Adjei,Jayanth Panyam,Jayanth Panyam,Sanja Dimitrijevic,Vinod Labhasetwar +7 more
TL;DR: Polymeric nanoparticles (NPs), based on poly(lactic-co-glycolic acid), that provide sustained intracellular delivery of plasmid DNA, resulting in sustained gene expression without vector-associated toxicity, are developed and may be developed as nonviral vectors for cancer and other genetic diseases.
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Evaluation of new rosin derivatives for pharmaceutical coating.
P. M. Satturwar,S. V. Fulzele,Jayanth Panyam,P. M. Mandaogade,D. R. Mundhada,B. B. Gogte,Vinod Labhasetwar,A. K. Dorle +7 more
TL;DR: Two new Rosin derivatives were synthesized and evaluated for physicochemical properties, molecular weight, polydispersity and glass transition temperature, and novel film forming materials with potential use in sustained drug delivery are proposed.
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Selective biophysical interactions of surface modified nanoparticles with cancer cell lipids improve tumor targeting and gene therapy
TL;DR: It is demonstrated that different surfactants, incorporated onto the NPs' surface, affect the biophysical interactions of NPs with the lipids of cancer cells and normal endothelial cells, which may hold promise for engineering targeted delivery of therapeutics.