Vladimir Brusic

TL;DR: This approach provides an experimental basis for the design of pathogen specific, T-cell epitope-based vaccines that are targeted to majority of the genetic variants of the pathogen, and are effective for a broad range of differences in human leukocyte antigens among the global human population.

TL;DR: Hidden Markov models (HMM) were combined with the successive state splitting (SSS) algorithm for optimization of the HMM structure, to predict peptide binders to the human MHC class II molecule HLA-DRB1*0101, demonstrating the high accuracy of predictions with the simplicity of implementation.

TL;DR: In this article, the physical presence of peptides eluted from HPV-16-transformed epithelial tumor HLA-A*0201 immunoprecipitates was analyzed by MS3 Poisson detection mass spectrometry.

TL;DR: FIMM database (http://sdmc.krdl.org.sg:8080/fimm ) contains data relevant to functional molecular immunology, focusing on cellular immunology.

TL;DR: Large-scale comparative analysis of proteins from avian and human strains is performed, to produce a catalogue of mutations associated with H2H transmissibility, and to detect their presence in avian isolates, which suggests human host adaptation appears to be complex and systemic, involving nearly all influenza proteins.