V
Vladimir Joukov
Researcher at Harvard University
Publications - 33
Citations - 11264
Vladimir Joukov is an academic researcher from Harvard University. The author has contributed to research in topics: Vascular endothelial growth factor & Vascular endothelial growth factor C. The author has an hindex of 29, co-authored 33 publications receiving 10862 citations. Previous affiliations of Vladimir Joukov include University of Helsinki.
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Journal ArticleDOI
A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases.
Vladimir Joukov,Katri Pajusola,Arja Kaipainen,Dmitri Chilov,Isto Lahtinen,Eola Kukk,Olli Saksela,Nisse Kalkkinen,Kari Alitalo +8 more
TL;DR: VEGF‐C is a novel regulator of endothelia, and its effects may extend beyond the lymphatic system, where Flt4 is expressed.
Journal Article
A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases (vol 15, pg 290, 1996)
Vladimir Joukov,Katri Pajusola,Arja Kaipainen,Dmitri Chilov,Isto Lahtinen,Eola Kukk,Olli Saksela,Nisse Kalkkinen,Kari Alitalo +8 more
Journal ArticleDOI
Hyperplasia of lymphatic vessels in VEGF-C transgenic mice
Michael Jeltsch,Arja Kaipainen,Arja Kaipainen,Vladimir Joukov,Vladimir Joukov,Xiaojuan Meng,Xiaojuan Meng,Merja Lakso,Merja Lakso,Heikki Rauvala,Heikki Rauvala,Melody A. Swartz,Melody A. Swartz,Dai Fukumura,Dai Fukumura,Rakesh K. Jain,Rakesh K. Jain,Kari Alitalo,Kari Alitalo +18 more
TL;DR: VEGF-C induces selective hyperplasia of the lymphatic vasculature, which is involved in the draining of interstitial fluid and in immune function, inflammation, and tumor metastasis, and may be of potential use in therapeutic lymphangiogenesis.
Journal ArticleDOI
Vascular endothelial growth factor B, a novel growth factor for endothelial cells.
Birgitta Olofsson,Katri Pajusola,Arja Kaipainen,G. von Euler,Vladimir Joukov,Olli Saksela,Arto Orpana,R F Pettersson,Kari Alitalo,Ulf Eriksson +9 more
TL;DR: The results suggest that VEGF-B has a role in angiogenesis and endothelial cell growth, particularly in muscle.
Journal ArticleDOI
Proteolytic processing regulates receptor specificity and activity of VEGF-C
Vladimir Joukov,Tarja Sorsa,Vijay Kumar,Michael Jeltsch,Lena Claesson-Welsh,Yihai Cao,Olli Saksela,Nisse Kalkkinen,Kari Alitalo +8 more
TL;DR: The role of post‐translational processing in VEGF‐C secretion and function is analysed, and novel structure–function relationships in the PDGF/VEGF family are revealed.